Development of molecules capable of binding to specific sequences of double-stranded (ds) DNA continues to attract considerable interest, as this can yield useful tools for applications in life science, biotechnology,...

Invader probes are additionally activated for recognition of mixed-sequence DNA targets upon incorporation of spermine bulges.

Major efforts have been devoted to the development of constructs that enable sequence-specific recognition of double-stranded (ds) DNA, fueled by the promise for enabling tools for applications in molecular biology,...