Background: Febrile convulsions is one of the most common type of seizures seen in children. It has been suggested that low serum magnesium (Mg) has occasionally been associated with epilepsy. A positive correlation of the hypomagnesemia with the severity of epilepsy was also found. The present study aimed to estimate the levels of serum magnesium in children with febrile convulsions and to compare serum magnesium levels with normal children.Methods: Fifty patients who were eligible after screening for inclusion and exclusion criteria were included in the study group after a signed written informed consent and 50 controls were also taken. A detailed history, clinical examination and these investigations were done – complete blood count (CBC) (Hb, DC and ESR), serum calcium, serum magnesium, serum electrolytes, random blood sugar and cerebrospinal fluid (CSF) analysis.Results: The serum magnesium level was normal in 45 patients (90%) with febrile convulsions, low levels in 4 cases (8%) and high levels seen in 1 case (2%). Serum magnesium levels were normal in all 50 controls. In this study, the serum magnesium levels has got no correlation in patients with febrile convulsion. So, routine magnesium supplementation need not be prescribed in normal subjects to prevent febrile convulsions.Conclusions: Routine measurement of serum levels of Mg, glucose and calcium are warranted in subject with febrile convulsions. However, large prospective studies are further required in future to establish the correlation of serum Mg and febrile convulsions so that a standard guidelines can be set up which could be followed universally.

PURPOSE: Cerebral palsy is a common pediatric neurological problem that has multiple comorbidities, including nutritional issues. Hematological and biochemical parameters significantly affect the health status of patients with cerebral palsy, and till now very few studies have analyzed these parameters. This study aimed to describe the hematological and biochemical parameters of children diagnosed with cerebral palsy. METHODS: This four-year observational study included children with cerebral palsy who were admitted to the Department of Pediatrics of a medical college teaching hospital. Hemoglobin, platelet count, white blood count (WBC), red blood cells (RBCs), packed cell volume, RBC indices, and biochemical parameters (urea, creatinine, total bilirubin, total protein, albumin, globulin, aspartate transaminase, alanine transaminase, electrolytes, calcium and alkaline phosphatase) were noted and values (mean, standard deviation, and interquartile range) presented. Age and gender-based analyses were performed. RESULTS: The average hemoglobin level was 11.48 mg/dl, platelet count was 301.24×109/L, and WBC count was 11.13 109/L. Anemia was observed more commonly in males younger than nine years of age. Of 282 patients, 14 (4.96%) had a platelet count of less than 150×109/L. Abnormal alkaline phosphatase levels were observed more commonly in patients who were younger than nine years of age and in females more than males, and the difference was statistically significant. Protein levels and calcium levels were similar between both age groups. CONCLUSION: Anemia was more common in younger patients and males with cerebral palsy. Abnormal bone turnover markers (alkaline phosphatase) were more common in young patients and females with cerebral palsy. Understanding the differential effect of age and gender on various investigational parameters will help improve care of children with cerebral palsy by initiating appropriate and timely clinical interventions, thereby providing a better quality of life.