Nanomaterials are indeed a nanoscale technology that deals with the creation, evaluation, fabrication, and utilization of systems at the nanometre scale by manipulating their size and shape. We consider natural polysaccharides such as promising polysaccharides, which are biodegradable, nontoxic, abundant, and inexpensive bio-polymeric precursors for preparing the materials of choice in various industries. The aim is to review different methods to produce hydrophobically modified Abelmoschus esculentus nanoparticles and study the evaluation processes of these nanoparticles as given in the literature. It proved the benefits of derivatives of gum by introducing different chemical groups. The chemical functionalization of gum mainly includes the esterification, etherification, and cross-linking reactions of the hydroxyl groups and contains a special fibre which takes sugar levels in the blood under control, providing a sugar quantity acceptable for the bowels. Okra contains mucilage that helps remove poisonous chemicals and bad cholesterol, often overloads the liver. Recovering from psychological conditions, like depression, general weakness, and joint healthiness, can be done with Okra. Someone additionally applied it for pulmonary inflammation, bowel irritation, and sore throat. Purgative properties okra possesses are beneficial for bowel purification. It is used to counteract the acids. Fibre okra contains is a valuable nutrient for intestinal microorganisms and ensures proper intestine functionality. It also protects the mucosa of the digestive tract by covering them with an extra layer because of its alkaline nature. Nanotechnology has emerged as a critical component of pharmaceutics, with many applications in drug carriers of interest aimed at improving drug clinical outcomes such as cancer, diabetes mellitus, wound care management, atopic dermatitis, cosmeceutical, etc and discussed briefly the beneficial outcomes of this review.

Nanotechnology is a progressing and novel technique in healthcare and smart drug delivery. There are many benefits and future aspects of nanogel containing nanoparticles in the advanced diagnosis, mitigation, and treatment of many important disorders with improved outcomes because of its particle size, high stability, biodegradability, biocompatibility, large surface area, and high drug charging capacity. Their small particle size provides the feature basis for drug charging capacity and for the swelling property to form a 3D structure with advantages, limitations, and classification of nanogels. The motive of the review article is to summarise the natural polymers such as Okra gum, Chitosan, Acacia gum, Pullulan, PLA, and PLGA that are employed to prepare nanogels comprising nanoparticles by the chemical crosslinking method. The various applications of these nanogels as nanoparticles in the many fields of healthcare, including local anesthetics, neurodegenerative, anti-inflammatory, vaccine delivery, transdermal delivery, ophthalmology, and diabetes. In this present review article, the author has focused on current trends of nanogel in nanomedicine, oilfield applications, food packing, cancer research, cosmeceutical, and biomedical applications.