BACKGROUNDMast cells have received little attention in leprosy, but evidence linking them with delayed-type hypersensitivity reactions raises the possibility that they may be of some importance in leprosy.

BACKGROUNDAbnormal uterine bleeding (AUB) is defined as a pattern of bleeding that does not correspond with the duration, amount and frequency of the flow of a normal menstrual cycle. It is one of the most common problems among patients presenting to Gynaecologists. There are a variety of causes leading to AUB, ranging from hormonal imbalance in young women in the reproductive age group to hyperplasia and malignancies in perimenopausal and postmenopausal patients. Analysis of endometrial biopsies by histopathology provides insight into cause of such bleeding and is important for diagnosis as a relatively less invasive procedure. Aims and Objectives-This study aims at histopathological analysis and at studying various patterns encountered in endometrial biopsies done for abnormal uterine bleeding in patients. MATERIALS AND METHODSThis study includes all patients who underwent endometrial biopsy for abnormal bleeding (other than for evaluation for infertility) from September 2016 to September 2017 after satisfying the specific inclusion and exclusion criteria. The biopsy specimens were obtained by Dilatation and Curettage or by biopsy and sent for histopathological examination. RESULTSA total of 71 biopsy specimens were selected of which 43 (60.5%) patients were premenopausal, 17 (23.9%) were perimenopausal and 11 (15.4%) were postmenopausal. Menorrhagia was the most common presenting complaint in 31 (43.6%) patients with AUB. Most common findings on histopathological examination were as follows: Secretory endometrium in 22 (30.9%), Proliferative endometrium in 14 (19.7%), Disordered Proliferative Endometrium in 11 (15.4%) patients followed by other patterns. Endometrial carcinoma was seen in 1 (1.2%) patient. CONCLUSIONStudy of endometrial histopathology in abnormal uterine bleeding is helpful and important to diagnose various disorders including hyperplasia and carcinoma of endometrium.