Purpose – The purpose of this paper is to verify the validity of a causal model that was made to predict the consumer’s acceptance of food additives. Design/methodology/approach – A new emotional model in which cognitive factors influence emotional factors from the bottom-up was made and the validity of the model was tested. A social survey was conducted in Tokyo, Japan, among 120 female undergraduate students. Findings – The results showed that the new emotional model had a higher validity than the conventional emotional model, in which emotional factors influence cognitive factors. Research limitations/implications – The reliability and validity of the present models should be reconfirmed with a sample of more than 200 subjects in the future. The sample comprised only Japanese female undergraduate students and additional studies be conducted with diverse samples to ensure that the proposed model is valid and reliable across multiple settings. Future studies should verify whether the use of other topics would produce the same results. Practical implications – As it is often difficult to directly affect consumer’s emotions by providing information and education for only a short period of time, it may be advisable to try to change consumer’s cognitions about the perceived risks and benefits through information and education instead. Social implications – The greater significance of the current study is the suggestion that the influence of perceptions on emotions should also be considered when evaluating consumer’s acceptance. Originality/value – This study showed that the influence of cognitive factors, such as perceived risk and perceived benefit, is also effective in an emotional model. This importantly suggests that consumer’s emotions like anxiety and anger can be changed by altering consumer’s cognitions or perceptions.

This is the first finding that chitosan/BmNPV bacmid DNA nanocomplexes can rival the performance of commercially available transfection reagents for the expression of recombinant proteins in Bm5 cells and silkworm larvae.

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The flow diverter has been shown to be a safe and effective device for large cerebral aneurysms in the proximal internal carotid artery (ICA). Recently, its indication has been expanded to small-and medium-sized cerebral aneurysms in the distal segment of the ICA. In this study, we report a singlecenter, retrospective investigation of the safety and efficacy of the Pipeline Flex device to treat these aneurysms. Of the patients who underwent Pipeline implantation for small-and medium-sized ICA aneurysms (! 12 mm) at our hospital between July 2013 and October 2021, 102 patients with 104 aneurysms were included in this study. The mean age of the patients was 57.7 ± 12.1 years, and 94 (90.4%) were female. The mean aneurysmal dome diameter was 9.2 ± 2.3 mm, the mean neck diameter was 5.3 ± 1.6 mm, and the mean dome-to-neck ratio was 1.8 ± 0.5. Twenty-five patients (24.0%) had incorporated vessels from the aneurysm. Complete occlusion of the aneurysms was obtained in 96 patients (92.3%). There were no cases of parent artery stenosis or major stroke after the procedure. Absence of incorporated vessel from the aneurysm dome and adjunctive coil embolization are statistically significant factors indicating complete occlusion in multivariate analysis. The time to complete occlusion was determined earlier with the use of the Pipeline Shield (p = 0.0386) and with adjunctive coils (p = 0.0025). We showed that Pipeline implantation for small-and medium-sized aneurysms was safe and highly effective.