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Epicardial fat may play an important role in the pathogenesis of coronary artery disease (CAD). We investigated the relationship between coronary artery ectasia (CAE) and epicardial fat volume (EFV). This retrospective study included 506 patients with CAE (group 1), 500 with CAD (group 2), and 500 patients with normal coronaries as controls (group 3). The pericardium was traced manually from the edge of the pulmonary trunk to the last measured by computed tomography slice containing images of the heart to obtain a region of interest. EFV was significantly higher in patients with CAD than in those with CAE (87.94 ± 22.18 vs 61.33 ± 12.75 mL; P < .001). Patients with normal coronaries had EFV of 56.62 ± 9.82 mL. Multivariate logistic regression analysis showed that male gender [Odds ratio (OR) (95% confidence interval (CI)): 1.220 (1.015–1.682), P = .042], diabetes [OR (95% CI): 1.036 (1.008–1.057); P = .002], and smoking [OR (95% CI): 3.043 (1.022–9.462); P = .005] were significantly associated with CAE. The receiver operating characteristic (ROC) curve showed that EFV had strongest diagnostic value for detecting CAD rather than CAE [AUC .502 P = .074 (95% CI: .311–.784)]. This study demonstrated that EFV is an independent predictor for CAE and CAD. However, sensitivity and specificity for detecting CAE is low when compared with CAD.

Objective: To determine the frequency and in-hospital mortality of right ventricular myocardial infarction, in patients with inferior wall myocardial infarction. Methods: This was a descriptive case series, conducted at Cardiology Department, Rehman Medical institute during time duration 18th Feb 2017 to 18th Aug 2017. The study was conducted after approval was obtained from the hospital ethical review committee. Sample selection was done through a non-probability consecutive sampling technique. Patients were included in the study based on inclusion and exclusion criteria. A detailed history was taken followed by a complete physical examination and ECG was done. Demographic and outcome data were noted on a predesigned Performa. Results: The mean age (SD) of patients in this study was 68±11.05 years. 94 (60.64%) patients were male while 61 (39.35%) patients were female. Among patients 142 (91.61%) were smokers, 136 (87.74%) patients were hypertensive and 123 (79.35%) patients were diabetic. A total of 155 patients were hospitalized with the diagnosis of acute inferior STEMI. Of the total 155 in-patients, 56(36.1%) were having right ventricular infarction. In-hospital mortality was recorded in 39/155(25.16%) patients during hospitalization having right ventricular myocardial infarction with inferior wall myocardial infarction. Conclusion: This study concluded that Right Ventricular Infarction can occur in patients with Inferior Wall Myocardial Infarction with certain adverse in-hospital outcomes such as mortality. Keywords: Coronary Artery Disease (CAD), Right Ventricle Infarction (RVI).