Food supply chain is a rapidly growing integrated sector and covers all the aspects from farm to fork, including manufacturing, packaging, distribution, storing, as well as further processing or cooking for consumption. Along this chain, smart packaging could impact the quality, safety, and sustainability of food. Packaging systems have evolved to be smarter with integration of emerging electronics and wireless communication and cloud data solutions. Although there are many factors causing the loss and waste issues for foods throughout the whole supply chain of food and there have been several articles showing the recent advances and breakthroughs in developing smart packaging systems, this review integrates these conceptual frameworks and technological applications and focuses on how innovative smart packaging solutions are beneficial to the overall quality and safety of food supply by enhancing product traceability and reducing the amount of food loss and waste. We start by introducing the concept of the management for the integrated food supply chain, which is critical in tactical and operational components that can enhance product traceability within the entire chain. Then we highlight the impact of smart packaging in reducing food loss and waste. We summarize the basic information of the common printing techniques for smart packaging system (sensor and indicator). Then, we discuss the potential challenges in the manufacturing and deployment of smart packaging systems, as well as their cost‐related drawbacks and further steps in food supply chain.
Soft crawling robots have attracted great attention due to their anticipated effective interactions with humans and uncertain environments, as well as their potential capabilities of completing a variety of tasks encompassing search and rescue, infrastructure inspection, surveillance, drug delivery, and human assistance. Herein, a comprehensive survey on recent advances of soft crawling robots categorized by their major actuation mechanisms is provided, including pneumatic/hydraulic pressure, chemical reaction, and soft active material‐based actuations, which include dielectric elastomers, shape memory alloys, magnetoactive elastomers, liquid crystalline elastomers, piezoelectric materials, ionic polymer–metal composites, and twisted and coiled polymers. For each type of actuation, the prevalent modes of locomotion adopted in representative robots, the design, working principle and performance of their soft actuators, and the performance of each locomotion approach, as well as the advantages and drawbacks of each design are discussed. This review summarizes the state‐of‐the‐art progresses and the critical knowledge in designing soft crawling robots and offers a guidance and insightful outlook for the future development of soft robots.
Polylactide (PLA) is the most widely utilized biopolymer in medicine. However, chronic inflammation and excessive fibrosis resulting from its degradation remain significant obstacles to extended clinical use. Immune cell activation has been correlated to the acidity of breakdown products, yet methods to neutralize the pH have not significantly reduced adverse responses. Using a bioenergetic model, we observed delayed cellular changes that were not apparent in the short-term. Amorphous and semi-crystalline PLA degradation products, including monomeric L-lactic acid, mechanistically remodel metabolism in cells leading to a reactive immune microenvironment characterized by elevated proinflammatory cytokines. Selective inhibition of metabolic reprogramming and altered bioenergetics both reduce these undesirable high cytokine levels and stimulate anti-inflammatory signals. Our results present a new biocompatibility paradigm by identifying metabolism as a target for immunomodulation to increase tolerance to biomaterials, ensuring safe clinical application of PLA-based implants for soft- and hard-tissue regeneration, and advancing nanomedicine and drug delivery.
Soft end effectors or grippers capable of grasping objects dexterously and efficiently have attracted increasing attention in a broad range of applications. This article describes a smart soft finger‐like actuator with fast response, accurate control, self‐powered pressure, and bending sensing capability by combing the cable‐driven actuation with soft triboelectric nanogenerators (TENGs). The soft actuator, driven by a miniature DC motor, is designed to have multiple segments of elastomer body split with triangular cuts to facilitate the bending actuation and conformal contact with target objects. Two types of TENGs are integrated with the soft actuator: a single‐electrode‐mode TENG to measure the contact pressure and an inner contact–separation‐mode TENG to detect the bending. With micropyramid structures, the tribo‐skin patches possess high sensitivity and good compatibility with the actuator and can actively detect proximity, contact, and pressure via self‐generated electricity. Based on the modular design approach, a gripper with three fingers is fabricated and tested for its grasping, sensing, and self‐powering performance. This gripper is capable of picking up different kinds of objects, providing sensory feedback, and generating electricity, which shows great potential for use in robot–human and robot–environment interaction applications.
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