Spilanthes acmella is an important medicinal plant, found in tropical and subtropical countries mainly India and South America. Popularly, it is known as toothache plant which reduces the pain associated with toothaches and can induce saliva secretion. Various extracts and active metabolites from various parts of this plant possess useful pharmacological activities. Literature survey proposed that it has multiple pharmacological actions, which include antifungal, antipyretic, local anaesthetic, bioinsecticide, anticonvulsant, antioxidant, aphrodisiac, analgesic, pancreatic lipase inhibitor, antimicrobial, antinociception, diuretic, vasorelaxant, anti-human immunodeficiency virus, toothache relieve and anti-inflammatory effects. This review is elaborately describing the traditional uses, phytochemistry, pharmacology, and toxicology of this plant. This review would assist researchers to search scientific information in the future.

Human Body Communication (HBC) has emerged as an alternative to radio wave communication for connecting low power, miniaturized wearable and implantable devices in, on and around the human body. HBC uses the human body as the communication channel between on-body devices. Previous studies characterizing the human body channel has reported widely varying channel response much of which has been attributed to the variation in measurement setup. This calls for the development of a unifying bio-physical model of HBC supported by in-depth analysis and an understanding of the effect of excitation, termination modality on HBC measurements. This paper characterizes the human body channel up to 1MHz frequency to evaluate it as a medium for broadband communication. A lumped bio-physical model of HBC is developed, supported by experimental validations that provides insight into some of the key discrepancies found in previous studies. Voltage loss measurements are carried out both with an oscilloscope and a miniaturized wearable prototype to capture the effects of noncommon ground. Results show that the channel loss is strongly dependent on the termination impedance at the receiver end, with up to 4dB variation in average loss for different termination in an oscilloscope and an additional 9 dB channel loss with wearable prototype compared to an oscilloscope measurement. The measured channel response with capacitive termination reduces low-frequency loss and allows flat-band transfer function down to 13 KHz, establishing the human body as a broadband communication channel. Analysis of the measured results and the simulation model shows that instruments with 50Ω termination impedance (Vector Network Analyzer, Spectrum Analyzer) provides pessimistic estimation of channel loss at low frequencies. Instead (1) high impedance (2) capacitive termination should be used at the receiver end for accurate voltage mode loss measurements of the HBC channel at low frequencies. The experimentally validated bio-physical model shows that capacitive voltage mode termination can improve the low frequency loss by up to 50dB, which helps broadband communication significantly.

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Successful rehabilitation of oropharyngeal swallowing disorders (i.e., dysphagia) requires frequent performance of head/neck exercises that primarily rely on expensive biofeedback devices, often only available in large medical centers. This directly affects treatment compliance and outcomes, and highlights the need to develop a portable and inexpensive remote monitoring system for the telerehabilitation of dysphagia. Here, we present the development and preliminarily validation of a skin-mountable sensor patch that can fit on the curvature of the submental (under the chin) area noninvasively and provide simultaneous remote monitoring of muscle activity and laryngeal movement during swallowing tasks and maneuvers. This sensor patch incorporates an optimal design that allows for the accurate recording of submental muscle activity during swallowing and is characterized by ease of use, accessibility, reusability, and cost-effectiveness. Preliminary studies on a patient with Parkinson’s disease and dysphagia, and on a healthy control participant demonstrate the feasibility and effectiveness of this system.

Radiative communication using electro-magnetic (EM) fields amongst the wearable and implantable devices act as the backbone for information exchange around a human body, thereby enabling prime applications in the fields of connected healthcare, electroceuticals, neuroscience, augmented and virtual reality. However, owing to such radiative nature of the traditional wireless communication, EM signals propagate in all directions, inadvertently allowing an eavesdropper to intercept the information. In this context, the human body, primarily due to its high water content, has emerged as a medium for low-loss transmission, termed human body communication (HBC), enabling energy-efficient means for wearable communication. However, conventional HBC implementations suffer from significant radiation which also compromises security. In this article, we present Electro-Quasistatic Human Body Communication (EQS-HBC), a method for localizing signals within the body using low-frequency carrier-less (broadband) transmission, thereby making it extremely difficult for a nearby eavesdropper to intercept critical private data, thus producing a covert communication channel, i.e. the human body. This work, for the first time, demonstrates and analyzes the improvement in private space enabled by EQS-HBC. Detailed experiments, supported by theoretical modeling and analysis, reveal that the quasi-static (QS) leakage due to the on-body EQS-HBC transmitter-human body interface is detectable up to <0.15 m, whereas the human body alone leaks only up to ~0.01 m, compared to >5 m detection range for on-body EM wireless communication, highlighting the underlying advantage of EQS-HBC to enable covert communication.