Background: Osteoporosis is a major public health problem as it is associated with substantial morbidity and socioeconomic burden.

Background- The diagnostic detection of malignant cells in effusions serves as a mainstream diagnostic tool and a predictor of the spread of diseases. Aim-To compare diagnostic efficacy of liquid based cytology (LBC) with conventional cytopreparatory techniques of pleural, peritoneal and pericardial fluids. Methodology - 110 peritoneal, pleural and pericardial effusions were received from indoor of various departments, microscopic examination was carried out by conventional and SurePath LBC method. For each case scoring was done for cellularity, cell morphology, distribution and background. They were classified as Non-neoplastic, suspicious for malignancy and malignant. Results - LBC showed better cell yield, morphology, distribution and background. Non-neoplastic lesions were maximum in number and constituted 78 (70.9%) cases, 8 (7.3%) cases were suspicious for malignancy, 22 (20%) malignant cases and 2 cases were unsatisfactory for evaluation. Conclusion- compared to conventional method, LBC was superior in making diagnosis.

Background : TB remains a major health concern world wide with extrapulmonary TB accounting for 20% cases in India. Tubercular lymphadenopathy is most common extrapulmonary manifestation in TB. Aim: To compare and analyse cytomorphology patterns, AFB positivity and CBNAAT for detection of tubercular lymphadenopathy Methodology: a total of 80 FNAC samples from lymph nodes were taken, one part was sent for CBNAAT and other part was used to prepare slides and stained with H& E, PAP, MGG, ZN stain for AFB. Results:Out of 80 cases, 52 (65%)were granulomatous, 14 (17.5%)each were of reactive and suppurative. Among these 52 cases reported as granulomatous 32 were positive for CBNAAT, 11 AFB positive . Only 1 case out of 14 reactive cases was positive for CBNAAT. Out of 14 suppurative cases, 4 cases were CBNAAT positive. Conclusion: CBNAAT is a rapid test, can detect even if bacilli is less in number but FNAC along with AFB is simple procedure in resource limited area.