Background : Poisoning is a serious emergency and a big problem that affects people of all ages all over the world. Education, demographics, socioeconomic conditions, customs, and local belief all influence the cause and kind of poisoning in different areas of the world and within the country. Poisoning patterns differ depending on age, the kind and amount of the poison, and the method of exposure.  Even while there has been no major drop in the number of unintentional poisonings, the pattern of poisoning has changed, with new risks always emerging as a result of the introduction of novel pharmaceuticals and chemicals for home use and agricultural. Objective : To asses the clinical Profile and outcome of Poisoning among Pediatric Population in a tertiary care hospital. Materials and Methods : The present  Prospective observational study conducted in Department of Pediatrics at Gadag Institute of Medical Sciences , between June 2020 to December 2021.   All children and adolescent who were admitted to pediatric intensive care unit with history of poisoning were included in this study.