Background :-Tuberculosis is a major public health problem in India and other developing countries. Extrapulmonary TB represents a greater diagnostic problem than pulmonary TB because it presents with less frequency and occurs with little liberation of bacilli, as well as the fact that it is localized in sites that are difficult to access. Aims of study:-1.To find out positivity of acid fast bacilli in aspiration smears of lymph nodes and other suspected tubercular lesions by Ziehl Neelson method and fluorescence method. 2. To evaluate the accuracy of fluorescent staining in the detection of Acid Fast Bacilli. Study design:-In a Prospective study for the period of 2 years i.e. 2012 to 2014. Method:-128 clinically suspected cases of tuberculous lesions attending the Department of Medicine, Surgery, ENT, Paediatrics, TB and Chest diseases were studied. Fine-needle aspiration was performed in these cases in the Department of Pathology at tertiary hospital, The results obtained after staining the smears using the Hematoxylin & Eosin stain, Papanicolaou stain, Ziehl-Neelsen stain and Auramine-Rhodamine fluorescent stain were evaluated Data was analyzed by SPSS version 10. Observation:-Out of 128 cases, 05 cases were diagnosed as reactive lymphadenopathy, 04 cases were acute suppurative inflammation and 04 samples were inadequate for evaluation. Statastical analysis of 115 samples was performed. A statistically significant difference was seen in the detection of acid fast bacilli by the AR stain, with a highly significant p value. AR stain had detected additional 17/115 (14.7%) cases which were ZN negative. Conclusions: The fluorescent microscopy using Auramine-Rhodamine stain detects more AFB as compared to conventional ZN stain.
A 40-year-old woman presented with insidious onset, gradually progressive dysarthria and inability to manoeuvre bolus of food in her mouth while eating. The duration of her symptoms was 3 months. On evaluation, the left half of her tongue was wasted. The tongue deviated to the left on protrusion. There were no clinical features suggestive of involvement of the ipsilateral 9th, 10th or 11th cranial nerves. MRI of the brain showed a large, fusiform lesion in the left hypoglossal canal, extending into the jugular canal. The lesion was surgically excised and found to be a schwannoma.
We report a 57-year-old man presenting with symptoms of sharp pricking, exertional retrosternal chest pain multiple times, each episode lasting for a few seconds. On evaluation, the ECG of the patient showed normal sinus rhythm with T wave inversions in leads V1-V3. Troponin T test was negative. Transthoracic echocardiography showed a globular mass in the interventricular septum. Cardiac MRI was suspicious of the lesion to be a hydatid cyst. Surgical excision of the lesion followed by histopathology was confirmatory of hydatid cyst.
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