Aim: To assess the hypothesis that coinfection with SARS-CoV-2 and S. aureus exacerbates morbidity and mortality among patients, the study Suleiman Shuaibu Adeiza 1 aims to report the pooled burden of S. aureus co-infections in patients hospitalized with COVID-19.
Aim:The purpose of the study was to identify common descriptors and publication hotspots that may form reference themes for future monkey pox research. Method: Bibliometric analysis of monkeypox related studies between 1962 and 2022 was carried out to ascertain and describe this body of literature. Results and conclusion: A total of 1,134 documents were analysed for bibliometric indicators. The studies had 3,478 authors, an average of 5.72 coauthors per publication and a 3.73 author collaboration index. Annual scientific production peaked in 2004 (5.5%) and 2020 (5.3%). Monkeypox research accumulated 128 grants, 68 policy documents, 9 clinical trials, and 50 patents. The United States placed first in terms of the number of documents and citations, followed by Germany with 73, United Kingdom with 53, Russia and the Democratic Republic of the Congo (DRC) with 34 documents each. The DRC and Nigeria had the most documents among African countries. Text mining showed researchers have put their efforts into studies related to infectious disease 'epidemiology': the 'emergence', 'Case diagnosis and 'surveillance' of 'outbreaks'. The top keywords were 'monkeypox' (570 times), 'monkeypox virus' (411 times), 'poxviridae infections' (332 times), 'small pox' (266 times), 'orthopox virus' (248 times), 'vaccinia virus' (203 times), and 'disease outbreaks' (179 times). The most cited treatment related noun phrases were 'tecovirimat' (brand name Tembexa), 'Cidofovir'/ 'CMX001' (Brincidofovir), 'ACAM2000' (imvanex vaccine) and 'Vaccinia' Immune Globulin ('VIG'). This result will serve as a foundation for future research, guiding decision-making in monkeypox research and therapy.
Marburg virus (MARV) is a pathogenic zoonotic RNA virus etiologic for Marburg virus disease (MVD), a severe hemorrhagic fever. This is a rare disease, with a high fatality rate, that spreads via infected blood or body fluids or indirectly via fomites (contaminated objects and substances such as clothed, beds, personal protective equipment, or medical equipments). A few vaccines to protect against MARV are undergoing clinical trials, but there is not yet an approved vaccine against this disease. Eventually, prevention and control guidelines should be adhered to rigorously to alleviate this infection. This bibliometric analysis aimed to harness narrative evaluation, emphasizing the significance of quantitative approaches and delineating the most thought-provoking concerns for researchers using VOSviewer software (Centre for Science and Technology Studies, Leiden University, the Netherlands). “Marburg Virus” OR “MARV” AND “Diseases” search criteria were used for the analysis of articles published between 1962 and 2022. Co-occurrence analysis was carried out, which characterized different thematic clusters. From this analysis, we found that 1688 published articles, and the number of publications increased across that period annually, with a growth rate of 8.78%. It is also conspicuous that the number of publications in the United States reached its acme during this period (i.e., 714 publications, accounting for 42.29% of the total), and the United States Army Medical Research Institute of Infectious Diseases published the most literature (i.e., 146 papers). Our study found that the three pre-eminent authors of Marburg virus papers were “FELDMANN, HEINZ“ of the National Institute of Allergy and Infectious Diseases, United States, “BECKER, STEPHAN” of the Philipps University of Marburg, Germany, and “GEISBERT, THOMAS W” of the University of Texas Medical Branch, United States. In this study we found that “JOURNAL OF VIROLOGY” has published the most pertinent literature, totaling 88 articles, followed by “The journal of Infectious Diseases”, which published 76 relevant papers, and “VIRUSES”, which published 52 corresponding papers. The most cited paper on the Marburg virus was published in Nature Medicine, with 522 total citations and 29 citations/year. Studies of the changing epidemiology and evolving nature of the virus and its ecological niche are required; breakthrough and implementation of the efficacious vaccine candidate(s), prophylaxis and therapeutic alternatives and supervision strategies, unveiling awareness-raising programs, and developing apposite and timely preparedness, prevention, and proactive control strategies are of utmost importance.
Aim: The aim of the study was to determine the prevalence of methicillinresistant Staphylococcus aureus (MRSA) obtained from the nasal cavity Shuaibu Suleiman Adeiza 1 of participants and investigate the antibiotic resistance profiles of the isolates from Sokoto state, Nigeria.
To identify the contribution and impact of Nigerian authors, institutions, and journal sources, assess the knowledge base, detect the trends regarding antimicrobial resistance research through bibliometric analysis. Methods: Data from a query of antimicrobial resistance (AMR) articles in the dimensions database (PubMed included) were subjected to bibliometric analysis . Bibliometric indicators, topic networks were established, and topic trends were analysed by frequency, relevance scores, and trends over time. Results and conclusion: A total of 0.2% of the papers on AMR published worldwide were written by authors or institutions from Nigeria. In 2021, publications grew by 13.6%, The vast majority of publications (57.18%) were in the field of medical and health sciences, with 2428 papers. The top journal for AMR papers with at least one Nigerian institution affiliation was African Journal of Clinical and Experimental Microbiology, which published 1.8% of these papers. Antimicrobial stewardship, clinical and laboratory practices on AMR, public health implications, traditional and molecular methods, and phytomedicine and drug discovery were prominent areas of focus for Nigerian researchers. This study provided a comprehensive overview of the AMR research output, highlighting the need of increased research capacity to address the burden of AMR in Nigeria. Because Nigeria is overly reliant on conventional methods of discovery and development, innovation is essential for the future of antibiotics.
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