Lactobacillus paracasei TD062 with high inhibitory activity ameliorated lipid metabolism, oxidative stress, glucose metabolism and the PI3K/Akt pathway in diabetic mice, and the effects were dose-dependent to some extent.

Due to the simpleness and high efficiency, single-stage object detectors have been widely applied in many computer vision applications . However, the low correlation between the classification score and localization accuracy of the predicted detections has severely hurt the localization accuracy of models. In this paper, IoU-aware single-stage object detector is proposed to solve this problem. Specifically, IoU-aware single-stage object detector predicts the IoU for each detected box. Then the classification score and predicted IoU are multiplied to compute the final detection confidence, which is more correlated with the localization accuracy. The detection confidence is then used as the input of the subsequent NMS and COCO AP computation, which will substantially improve the localization accuracy of models. Sufficient experiments on COCO and PASCAL VOC datasets demonstrate the effectiveness of IoU-aware single-stage object detector on improving model's localization accuracy. Without whistles and bells, the proposed method can substantially improve AP by 1.7% ∼ 1.9% and AP75 by 2.2% ∼ 2.5% on COCO test-dev. On PASCAL VOC, the proposed method can substantially improve AP by 2.9% ∼ 4.4% and AP80, AP90 by 4.6% ∼ 10.2%. The source code will be made publicly available.

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