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Background: Acute coronary syndrome (ACS) refers to clinical symptoms pertaining to acute myocardial infarction. Bilirubin is an antioxidant that helps in removal of excessive heme. The aim of the study was to find the association of ACS and other risk factors for ACS with the total bilirubin levels in our setup.Methods: A cross sectional observational study was conducted on 100 cases attending the department of medicine in a Dr. Panjabrao Deshmukh Memorial Medical College, Amravati, Maharashtra. Patients fitting the eligibility criteria were subjected to data collection which was done using pre-designed case record form. The case record form had details of demography, detailed clinical history, physical examination and relevant investigations.Results: The mean age of the cases was 55.64±10.23 years with male preponderance. Majority of the patients presented with chest pain (83%) followed by shortness of breath (65%) and nausea/vomiting (33%). There was moderate significant correlation between total bilirubin levels and LDL levels (r=0.703; p value<0.001) and There was mild significant correlation between total bilirubin levels and TGs (r=0.403, p value<0.001) Based on the median value of 0.48 as cut off, 33% had bilirubin levels more than 0.48. Presence of diabetes and hyperlipidemias had significant association with the total bilirubin levels.Conclusions: Nearly 1/3rd of the patients in our study had high bilirubin levels. Higher bilirubin levels correlated well with presence of diabetes and presence of hyperlipidemias.  There was significant correlation between the serum LDL and TG levels with total bilirubin levels in the present study.

Background: Dengue is a mosquito borne acute febrile illness caused by viruses belonging to group flaviviridea. Primarily this disease is transmitted by Aedes aegypti and Aedes albopictus. There are 4 serotypes of dengue virus i.e. DENV 1, 2, 3, and 4. According to World Health Organization (WHO) report in 2009, globally around 2.5 billion people live in dengue endemic areas and more than 50 million people are infected with dengue fever annually. Dyselectrolemia is very common among dengue patients. Many studies found that hyponatremia is common in Dengue, DHF and especially in dengue shock patients. The purpose of this study was to evaluate serum sodium as the predictor of prognosis in dengue fever.Methods: Present study was longitudinal in nature conducted on 100 dengue patients. All patients fulfilling inclusion criteria and exclusion criteria were taken up for the study. Study was carried from August to October 2020. Serum electrolyte kit was used to analyze electrolytes.Results: Majority (39%) of the dengue patients was in the age group of 18-35 years and most of them were male. Fever was the most common complaint, present in all (100%) the patients followed by myalgia (96%), headache (89%), retro-orbital pain (88%), rash (73%) and joint pain (71%). Hyponatremia was the chief electrolyte abnormality, present among 61% dengue patients and it was associated with poor prognosis.Conclusions: We have found that hyponatremia was the chief electrolyte abnormality among dengue patients and prognosis was inversely related to hyponatremia.

Brakes are the integral part of a vehicle, which are used to reduce the speed of the car. Brake failure is one of the major problems, which lead to several accidents. Brake failure occurs due to brake lining fails, which leads to pressure loss. This mainly occurs in pneumatic brakes, which are used in most of the vehicles. The aim of our paper is to diagnose the faulty braking system and to enable the functioning of auxiliary braking or secondary brake system during brake failure. When the primary pneumatic brake fails the pressure sensor detects the brake failure and gives warning signal to the driver and also enables the auxiliary brake, which can be controlled by the driver manually through a manual control board. This braking system ensures the safety of the driver as well as the passengers without causing any damage to the vehicle.