It was found that a catalyst system RuCl2(PPh3)3/Xantphos is effective to install hydroxyethyl groups to the nitrogen atom of cyclic amines. Thus, the reactions of cyclic amines with ethylene glycol were performed in the presence of the RuCl2(PPh3)3/Xantphos catalyst in toluene at 120 °C for 22 h to provide the corresponding -amino alcohols in up to 92% yield.
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