We study the Kondo effect in a semiconductor quantum dot in contact with a spin-accumulated lead. The spin accmulation in a nonmagnetic semiconductor is realized by spin injection from a spin-polarized quantum point contact in combination with magnetic focusing, thus creating spin-unbalanced chemical potentials. We demonstrate that the spin splitting of the Kondo densities of states (DOS) for spin-up and spin-down electrons can be controlled by selectively shifting only the spin-up DOS using spin accumulation. We also show the possibility to recover the Kondo effect in a high magnetic field, by compensating for Zeeman splitting by spin accumulation.
Neural interfaces that directly measure brain activity are increasingly employed to elucidate large-scale brain networks and treat intractable neurological disorders. Considering the softness of brain tissue, current efforts to study chronic disorders aim to minimize invasiveness. We discuss recent progress on flexible neural interfaces with high durability under bending and stretching achieved by using organic materials. Multichannel microelectrodes are usually fabricated on thin polymer substrates as sheets and needles to reach superficial and deep brain structures, respectively. An interesting recent trend is the integration of high-density microelectrodes to measure detailed brain functions. The use of numerous measurement points (the current highest values achieved are 62 500 electrodes cm -2 and 3072 channels) can increase the accuracy of brain state estimation. However, further improvement should be devised for integration in plane considering the density of 250 000 neurons cm -2 in approximate intervals of 20 µm. Meanwhile, the ultimate goal of improving flexibility in neural interfaces is long-term implantation. Widely used approaches for thinning polymers (∼1 µm) and reducing the rigidity of neural interfaces compromise robustness due to high gas permeability and water uptake. We quantitatively analyze the technical proficiency of flexible neural interfaces in vivo regarding microelectrode integration and robustness. The solution contact impedance, which is a crucial factor in microelectrode miniaturization, is exhaustively surveyed and compared across PEDOT:PSS, Au, Pt, Pt black, IrOx, gels, and other components that should be designed within the permissible source impedance for the measurement device to ensure high-accuracy and low-noise measurements of brain activity in the order of microvolts. Furthermore, we detail a multifunctional neural interface with stretchability, optical transparency, easy intraoperative handling, and flexible transistor implementation for building an active electrode array, providing a new approach for flexible interfaces in neuroscience and neuroengineering.
Flexible and transparent electrodes are highly useful in wearable optoelectronic systems for healthcare and biosensing applications for conducting multimodal assessments with electrophysiological and optical measures. In such systems, the electrodes should exhibit a low sheet resistance, high visible transmittance, and small feature size, for reliable electrical sensing, optical observation of attached objects, and integration of devices for mapping local biology events, respectively. Herein, fine-printed, flexible, and transparent microelectrodes that allow biosensing and device integration are reported. The microelectrodes containing cross-aligned silver nanowire (AgNW) networks are patterned via a selective wetting deposition technique on a 1 μm-thick polymer substrate. A low sheet resistance of 25 Ω sq À1 and a visible transmittance of 96%-99% are achieved with a small pattern width of 25 μm. The biosensing application is demonstrated by detecting the leaf electric potential; the leaf cells under the microelectrodes are observed because of visible transparency. Furthermore, device integration is demonstrated by electronic circuits with ultrathin and transparent organic transistors. The transistors exhibit white-light illumination stability and mechanical stability to bending stress. These demonstrations provide a basis for developing ultraimperceptible wearable sensor systems with ultrathinness and high visible transmittance.
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