Spectroscopy and its imaging techniques are now popular methods for quantitative and qualitative analysis in fields such as agricultural products and foods, and combined with various chemometric methods. In fact, this is the application basis for spectroscopy and spectral imaging techniques in other fields such as genetics and transgenic monitoring. To date, there has been considerable research using spectroscopy and its imaging techniques (especially NIR spectroscopy, hyperspectral imaging) for the effective identification of agricultural products and foods. There have been few comprehensive reviews that cover the use of spectroscopic and imaging methods in the identification of genetically modified organisms. Therefore, this paper focuses on the application of NIR spectroscopy and its imaging techniques (including NIR spectroscopy and hyperspectral imaging techniques) in transgenic agricultural product and food detection and compares them with traditional detection methods. A large number of studies have shown that the application of NIR spectroscopy and imaging techniques in the detection of genetically modified foods is effective when compared to conventional approaches such as polymerase chain reaction and enzyme-linked immunosorbent assay.
The performances of RIETE, VTE-BLEED, SWITCO65 + , and Hokusai-VTE scores for predicting major bleeding events in hospitalized elderly cancer patients with venous thromboembolism (VTE) have not been evaluated. This study validated the performances of these scoring systems in a cohort of elderly cancer patients with VTE. Between June 2015 and March 2021, a total of 408 cancer patients (aged ≥ 65 years) with acute VTE were consecutively enrolled. The overall rates of in-hospital major bleeding and clinically relevant bleeding (CRB) were 8.3% (34/408) and 11.8% (48/408), respectively. RIETE score could categorize patients with increasing rate of major bleeding and CRB into low-/intermediate- and high-risk categories (7.1 vs. 14.1%, p = 0.05 and 10.1 vs. 19.7%, p = 0.02, respectively). The discriminative power of the four scores for predicting major bleeding was poor to moderate, indicated by areas under the receiver operating characteristic curves (0.45 [95% confidence interval, CI: 0.35–0.55] for Hokusai-VTE, 0.54 [95% CI: 0.43–0.64] for SWITCO65 + , 0.58 [95% CI: 0.49–0.68] for VTE-BLEED, and 0.61 [95% CI: 0.51–0.71] for RIETE). RIETE score might be used to predict major bleeding in hospitalized elderly cancer patients with acute VTE.
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