Smaller incision cataract surgery led to early recovery of visual function in the short term and less induced astigmatism in the long term.

No abstract

SUMMARY We report seven cases of subretinal neovascularisation with inferior posterior staphyloma. The upper border of the shallow staphyloma, detected by B-mode echography, invaded the macular area, and there was a neovascular net at the edge of the staphyloma. Three of the cases showed chorioretinal atrophy at the upper edge of the staphyloma in the same location as the neovascular net. Our cases were identical to those of subretinal neovascularisation in high myopic eyes in which the rupture of Bruch's membrane was related to the deformity of the scleral shell. As our cases included not-high-myopic eyes, the results suggest that the identical mechanism might be involved in the occurrence of neovascular maculopathy in the pathological high myopic eye and in the not-high-myopic eye with posterior staphyloma. Localised inferior posterior staphyloma may be an important cause of 'idiopathic' subretinal neovascularisation.Subretinal neovascularisation is triggered by the rupture of Bruch's membrane in the posterior fundus. ' High myopia has been described as a cause of subretinal neovascularisation,2 as have aging, trauma, uveitis, angioid streaks, and macular dystrophies. In the high myopic eye the uvea and retina at the posterior fundus expand so that the axial length of the eye is elongated. This condition leads to the rupture of Bruch's membrane and the growth of subretinal neovascularisation.1 However, when a localised posterior staphyloma exists, the posterior fundus may expand somewhat without significant elongation of the axial length. For example, the tilted disc syndrome is not necessarily associated with high myopia but has the typical high myopic fundus in the lower half of the eye related to the inferior staphyloma.45 In such a case myopic pathological complications may occur inside the posterior staphyloma even if the eye is not high myopic.We report here a series of consecutive cases with subretinal neovascularisation that are not severely high myopic but have inferior posterior staphylomas in order to study the relationship between the inferior staphyloma and subretinal neovascularisation.Correspondcncc to Shunji Tsuboi, MD,

Transport of Na and Cl across the isolated dog retinal pigment epithelium (RPE) choroid was investigated. Under the short-circuit condition, a net Na flux was observed from choroid to retina and a net Cl flux was determined in the opposite direction. The current created by the net flux of these two ions was larger than the short-circuit current (SCC). Addition of 10(-5) M ouabain to the apical side inhibited net fluxes of both Na and Cl, whereas it reduced the SCC 84%. Addition of 10(-4) M furosemide to the apical side inhibited net Cl flux but had no effect on the net Na transport. The 10(-4) M furosemide reduced the SCC 38%. These drugs had no effect when applied to the basal side. Thus the transport of both Na and Cl depends on the Na-K-ATPase in the apical membrane of the dog RPE. A furosemide-sensitive neutral carrier at the apical membrane is suggested for the transport of Cl. Replacement of HCO3 with SO4 in the bathing solution caused an increase in the SCC, indicating the choroid-to-retina movement of HCO3 across the short-circuited dog RPE choroid.

No abstract