No abstract

In the presence of 10 mol% lanthanide amide [(Me 3 Si) 2 N] 3 Ln(µ-Cl)Li(THF) 3 , the aza-Henry reaction of N-tosyl imines with nitroalkanes (1∶5 molar ratio) could be performed in good yields. The lanthanide amide-catalyzed aza-Henry reaction has the features of mild reaction conditions, tolerance of a variety of aromatic aldehyde-derived imines and nitroalkanes, short time and good chemical yields. A catalytic mechanism for the reaction was also proposed.

No abstract