Background: Developmental language disorders (DLDs) are the most common developmental disorders in children. For screening DLDs, speech ability (SA) is one of the most important indicators. Methods:In this paper, we propose a solution for the fast screening of children's DLDs based on a comprehensive SA evaluation and a deep framework of machine learning. Fast screening is crucial for promoting the prevalence and practicality of DLD screening which in turn is important for the treatment of DLDs and related social and behavioral abnormalities (e.g., dyslexia and autism). Our solution is focused on addressing the drawbacks existing in the previous DLD screening methods which include test failure due to text-based inducing material design and illiteracy of most young children, incomplete language evaluation indicators, and professional-reliant evaluation procedures. First, to avoid test failure, a novel comprehensive inducing procedure (CIP) with non-text (i.e., audio-visual) stimulus materials was designed that could cover a large range of modalities to adequately explore the comprehensive SA of the subjects. Second, to address incomplete language evaluation, a set of comprehensive evaluation indicators with full consideration of the characteristics of the children's language acquisition is proposed; furthermore, to break the professionalreliant limitation, we specifically designed a deep framework for fast and accurate screening.Results: Experimental results showed that the proposed deep framework is effective and professional with a 92.6% accuracy on DLD screening. Additionally, to provide a benchmark for the novel problem, we provide a CIP dataset with about 2,200 responses from over 200 children, which may also be useful for further DLD studies and insightful for the fast screening design of other behavioral abnormalities.Conclusions: Fast screening of children's DLDs can be achieved at accuracy up to 92.6% by our proposed deep learning framework. For successful fast screening, an elaborated CIP with corresponding comprehensive evaluating indicators is necessary to be designed for children suspected to have DLDs.

Catchy utterances, such as proverbs, verses, and nursery rhymes (i.e., “No pain, no gain” in English), contain strong-prosodic (SP) features and are child-friendly in repeating and memorizing; yet the way those prosodic features encoded by neural activity and their influence on speech development in children are still largely unknown. Using functional near-infrared spectroscopy (fNIRS), this study investigated the cortical responses to the perception of natural speech sentences with strong/weak-prosodic (SP/WP) features and evaluated the speech communication ability in 21 pre-lingually deaf children with cochlear implantation (CI) and 25 normal hearing (NH) children. A comprehensive evaluation of speech communication ability was conducted on all the participants to explore the potential correlations between neural activities and children’s speech development. The SP information evoked right-lateralized cortical responses across a broad brain network in NH children and facilitated the early integration of linguistic information, highlighting children’s neural sensitivity to natural SP sentences. In contrast, children with CI showed significantly weaker cortical activation and characteristic deficits in speech perception with SP features, suggesting hearing loss at the early age of life, causing significantly impaired sensitivity to prosodic features of sentences. Importantly, the level of neural sensitivity to SP sentences was significantly related to the speech behaviors of all children participants. These findings demonstrate the significance of speech prosodic features in children’s speech development.

Diffuse correlation spectroscopy (DCS) was used to measure resting‐state cerebral blood flow (CBF) in temporal lobes of children with autism spectrum disorder (ASD) and typically developing (TD) children. 22 children with ASD and 34 age‐matched TD children were recruited to participate in the experiment. DCS signals were recorded with 3 long source‐detector (SD) channels (SD distance = 22.0 mm) and 1 short SD channel (SD distance = 10.5 mm) from each side of the temporal lobe. Significant difference in CBF between left and right hemispheres was observed in ASD group, but not in TD group. With the degree of CBF lateralization as a discrimination feature, a leave‐one‐out ROC curve was plotted with the area‐under‐curve (AUC) value of 0.731 ± 0.010, indicating children with ASD could be discriminated from TD children. This suggested CBF lateralization in temporal lobes measured with DCS might serve as a discriminative feature for ASD.This article is protected by copyright. All rights reserved.