α,α-Difluoromethyl carbinols are important structural motifs in many therapeutic agents and functional materials. Herein, we developed a sustainable and efficient method for the synthesis of a series of α,α-difluoromethyl carbinols...

A mild, selective and redox-neutral Cp*Ir(III)- and Cp*Rh(III)-catalyzed C-H activation/annulation of salicylaldedydes with fluorovinyl tosylates is reported. The use of mono-fluorovinyl tosylate favors C2- and C3-substitution-free chromones synthesis via C-H...