The term, fibro-osseous lesions, is used for a group of pathological disturbances encompassing developmental, reactive or dysplastic lesions and neoplasms characterized by replacement of normal bone architecture by tissue composed of collagen fibers and fibroblasts containing various amount of calcified tissue. The groups of the fibro-osseous lesions are best considered as a spectrum of processes arising from cells in the periodontal ligament. Juvenile ossifying fibroma (JOF) is a benign, but potentially aggressive, fibro-osseous tumor of the craniofacial bones. This uncommon neoplasm is distinguished from other fibro-osseous lesions primarily by its age of onset, clinical presentation, potential behavior and the high tendency to recur. Clinically presenting as an actively growing lesion. Histopathologically consists cell rich fibrous stroma containing bands of cellular osteoid without osteoblastic lining together with trabeculae of more typical woven bone. Pathogenesis of JOF may be related to mutations of HRPT2 gene which may arises due to haploinsufficiency of the HRPT2 gene. Here, we reported a case of trabecular JOF (TJOF) which had variations in clinical, radiographic features and histopathological characteristics and it's etiopathogenesis in detail. How to cite this article Kadam R, Patel S, Pathak J, Swain N, Kumar S. Trabecular Juvenile Ossifying Fibroma of the Craniofacial Skeleton: Etiopathogenesis and a Case Report of the Rare Entity. J Contemp Dent 2014;4(1):51-55.

Focal cemento-osseous dysplasia (FCOD) is a benign fibroosseous condition that can be seen in dentulous and edentulous patients. It is an asymptomatic lesion and needs no treatment; however, follow-up is essential due to the possibility that it can progress to a condition called florid cemento-osseous dysplasia. Clinically, the lesion resembles periapical pathosis of odontogenic origin. FCOD is an asymptomatic lesion and occurs in the periapical area of teeth with vital pulps or in regions of extractions. The lesion is detected only on radiographic examination varying from completely radiolucent to densely radiopaque. The histopathologic appearance consists of trabeculae of bone and cementum like material present within a vascular fibrous stroma. Presented here is a case of FCOD in the mandible that occurred in the periapical region of a vital tooth. How to cite this article Kadam R, Patel S, Pathak J, Swain N, Kumar S. Focal Cemento-osseous Dysplasia. J Contemp Dent 2013;3(2):112-115.

Juvenile ossifying fibroma considered as a variant of ossifying fibroma by some authors is rare. Its aggressive behavior necessitates early detection and proper surgical management. It may mimic different pathologic entities of jaw at different stages. A case report of juvenile aggressive ossifying fibroma in a 12-year-old girl which was diagnosed, investigated and treated successfully is presented here.