Spin-wave nonreciprocity arising from dipole-dipole interaction is insignificant for magnon wavelengths in the sub-100 nm range. Our micromagnetic simulations reveal that for the nanoscale magnonic crystals studied, such nonreciprocity can be greatly enhanced via synthetic antiferromagnetic coupling. The nonreciprocity is manifested as highly asymmetric magnon dispersion curves of the magnonic crystals. Furthermore, based on the study of the dependence of the nonreciprocity on an applied magnetic field, the antiparallel alignment of the magnetizations is shown to be responsible for the enhancement. Our findings would be useful for magnonic and spintronics applications.
Not only dose oral administration have the highest safety, convenience and patient compliance, but also can improve patients' quality of life and reduce health care costs in many cases when compared to the parenteral route. However, many drugs, especially most anticancer drugs such
as paclitaxel (PTX), are not orally bioavailable, which is attributed to low aqueous solubility, poor intestinal permeability, and the high level of P-glycoprotein (P-gp) efflux. In this study, we developed a nano-porous silica aerogel delivery system for oral administration of PTX that improved
the bioavailability, reduced the side effects of the drug and inhibited tumor growth. The advantages of nano-porous silica aerogel include very high porosities, vast specific surface areas, high drug-loading rate, high biological safety, excellent biocompatibility, and biological inertia,
which can also be applied to a variety of drugs. The aerogel delivery system is a universal pharmaceutical system that has huge potential in the field of pharmacy.
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