A novel electrochemical cross-dehydrogenative C–S bond coupling of aryl thiols with 2H-indazole is reported. Thiol-functionalized 2H-indazoles were synthesized under catalyst-, oxidant-, and metal-free conditions with innocuous hydrogen as the sole byproduct at ambient temperature. Furthermore, continuous electrochemical flow conditions using a graphite/Ni flow cell were used to obtained 3-(arylthio)-2H-indazole compounds on a gram scale within the residence time of 39 min. Detailed mechanistic studies including control experiments and cyclic voltammetry are provided to support the radical–radical cross-coupling pathway.

No abstract

Abstract.Results pertaining to the response of the equatorial and low latitude ionosphere to a major geomagnetic storm that occurred on 15 May 2005 are presented. These results are also the first from the Indian zone in terms of (i) GPS derived total electron content (TEC) variations following the storm (ii) Local low latitude electrodynamics response to penetration of high latitude convection electric field (iii) effect of storm induced traveling atmospheric disturbances (TAD's) on GPS-TEC in equatorial ionization anomaly (EIA) zone.

Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA = N,N-diisopropylethylamine.