The net charges (at pH 7.4) of the ribosomal proteins (r-proteins) that comprise the
S10-spc
cluster show an inverse relationship with the halophilicity/halotolerance levels in both bacteria and archaea. In non-halophilic bacteria, the
S10-spc
cluster r-proteins are generally basic (positively charged), while the rest of the proteomes in these strains are generally acidic.
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