Background: Main stay of treatment of acute Bronchiolitis is general supportive care, such as oxygenation, aspiration of respiratory tract secretions, and hydration therapy. Recent research indicates that breathed hypertonic saline is a potential treatment. Objective: To compare the mean length of hospital stay and clinical bronchiolitis score of salbutamol nebulized in normal saline versus hypertonic saline in children with acute bronchiolitis. Material and methods Study Design: Randomized controlled design Setting: Department of pediatrics, Fatima Memorial Hospital, Lahore. Duration of Study: 6 months after approval of the study i.e. from 12th April 2017 to 12th October 2017. Data Collection Procedure: Relevant parameters were identified, and the CBSS was computed. Using random tables, cases were divided among two groups and given salbutamol or hypertonic saline nebs. The length of stay was determined. The Clinical Bronchiolitis Severity Score (CBSS) was recorded based on various variables. Version 17 of the statistical package for social sciences was used for statistical analysis. Result: Patients in the salbutamol group had a mean age of 13.56.66 months, while those in the hypertonic saline group had a mean age of 12.46.58 months. In the group receiving salbutamol, there were 29 males and 31 females. There were 32 men and 28 women in the hypertonic saline group. After 24 hours, the mean CBSS in the salbutamol group was 6.132.47, whereas in the hypertonic saline group, it was 4.881.75. After 24 hours of treatment, the difference in CBSS was significant between the two groups (P0.05). The mean duration of hospitalization was 3.920.81 days with salbutamol and 3.050.77 days with the hypertonic group. In both groups, there was a marked difference in duration of hospital stay (P0.05). Conclusion: Thus, hypertonic saline was more effective than salbutamol in reducing the CBSS score and duration of hospital stay. Keywords: Hospital Stay, Clinical Bronchiolitis Score, Nebulized Salbutamol, Normal Saline, Hypertonic Saline, Children, Acute Bronchiolitis.
Objective: To compare the frequency of complications (hyperthermia, skin eruption, dehydration) of LED phototherapy and fluorescent phototherapy in management of indirect hyperbilirubinemia in neonates Material and methods: This randomized control study was carried out from 1st June 2015 to 31 December 2016 at NNU of The Children`s Hospital Lahore using Non probability consecutive sampling technique after getting informed consent from parents. All basic demographic information of each variable (name, age) was noted and entered on Performa. SPSS-18 was used to interpret the data. Results: In our study the mean age was 1.98±0.83 days. Skin rash complication was observed in 43(13%) cases, dehydration was found in 48(14.5%) cases and hyperthermia was noted in 65(19.70%) patients. Practical Implication: Many setups in Pakistan are still using conventional fluorescent phototherapy machines. LED has lesser side effects as compared to conventional one so by using LED light source we can lessen the adverse effects of phototherapy that will be beneficial to the babies Conclusion: LED light source is effective for phototherapy with significantly lesser complication rate (hyperthermia, skin eruption, and dehydration) compared to fluorescent phototherapy in management of indirect hyperbilirubinemia in neonates. In this study LED phototherapy significantly showed fewer complications as compared to fluorescent phototherapy cases. Keywords: LED, Fluorescent, Hyperthermia, Skin, Rash, Dehydration, Neonates, Hyperbilirubinemia
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