Objectives: Breast cancer is the most common cancer among the female population in the world. Socioeconomic and cultural factors are important, as underdeveloped countries have high mortality rates due to deficiencies in prevention and early detection. Thus, the objective is to verify whether there is a direct relationship between the number of deaths due to breast cancer and social indicators. Methodology: A descriptive study with the analysis of the secondary data on mortality from malignant breast neoplasms, relating them to social indicators of schooling, age, and color/race between the years 2010 and 2019 in the state of Goiás and in Brazil, was analyzed. The data were extracted from the Mortality Information System (SIM), ordered, and tabulated using Excel. Results: Socioeconomic factors, such as education, age group, race, and geographic region, were considered conditioning factors for inequalities for such neoplasia. Groups with lower socioeconomic status showed high mortality rates, either due to later diagnoses or due to greater difficulty in accessing appropriate treatments. In contrast, the population inserted in favored socioeconomic scenarios presented, at the same time, high mortality rates, not only in Goiás, but also in the Brazilian scenario in general. This situation resulted, above all, from the insertion of this female portion in the labor market and, consequently, from the acquisition of new habits and behaviors. Conclusion: Different variables related to socioeconomic and cultural conditions have a direct influence on the occurrence of breast cancer in women in the state of Goiás and also in Brazil. In summary, people in disadvantaged situations tend to have high mortality rates for not having access to financing health conditions, while the wealthier population also has high rates due to cultural factors and related to new habits and behaviors that are factors risk.

Objectives: Breast cancer is the main neoplasm affecting women, and in many cases, curative treatment is not feasible. In this context, it is important to work with other forms of assistance that provide symptom relief and better quality of care for these patients. Therefore, the objective of this work is to portray the importance of attention and care to patients with breast cancer, whose cure is not possible, since it generates better acceptance of the situation and a more humanized end, with less suffering, pain, and anguish. Methodology: This is a descriptive research carried out based on a review of the medical literature available through a survey of publications from the past 12 years in the PubMed, Lilacs, and MedLine databases. The following descriptors were used: palliative care, home care, and breast cancer. Results: From the analysis performed, it can be seen that approximately 30% of patients diagnosed with breast cancer have some depressive disorder. This fact occurs due to the shock of the news of having an extremely serious disease, due to the disorders arising from the treatment or the progression of the disease itself. When assessing patients with breast cancer, who have palliative care at home, this percentage drops to approximately 9%, meaning an abrupt improvement in the quality of life of these people, resulting from multiprofessional home treatment. Conclusion: Given this situation, it is observed that home care, though insufficiently explored, has a good response for terminally ill patients. Therefore, it appears that palliative care should be better explored by both the public and private health systems, as this tool is capable of mitigating the adversities caused by cancer and improving the quality of life of patients and their families in this difficult stage.

Introduction/Objectives: Breast cancer is one of the most common malignancies among women, with 10% resulting from genetic predisposition. Li-Fraumeni syndrome is an autosomal dominant disease that predisposes to multiple primary tumors and is responsible for less than 0.1% of breast cancers, being considered in early-onset tumors. The aim of this report was to describe a fast evolution of three primary tumors in a young patient with Li-Fraumeni syndrome, including ductal breast carcinoma. Case Report: In 2017, a 27-year-old female patient was diagnosed with malignant cancer of the right breast, Luminal HER KI67 70%, clinical stage IV (liver and lung), underwent first-line cancer treatment, maintaining endocrinotherapy and Double Block, with a positive genetic panel test for TP53 mutation, inferring SLF. In 2018, screening colonoscopy showed colon adenocarcinoma, pT53pN1, treated with total colectomy with ileal pouch, followed by suspension of endocrinotherapy and maintenance of Double Block and adjuvant FOLFOX. At the end of chemotherapy, endocrinotherapy was adopted again. Reassessment tests showed partial response in the liver, but the primary nodules were unchanged. Biopsy after thoracoscopy described lung adenocarcinoma, pT3pN2, submitted to adjuvant with Gemzar and Navelbine, followed by Double Block and interruption of endocrinotherapy. It evolved with the appearance of nodules in the right breast, suggestive of progression of breast disease, under treatment with Xeloda, Herceptin, and Perjeta, showing good clinical response. Discussion: Breast cancer in young people increases the possibility of heredity, thus raising the need for investigations of genetic syndromes. Although rare, the identification of FHL brings an important implication for the genetic counseling. Early diagnosis is the best form of management, enabling the preventive screening and intervention of multiple malignancies. Conclusion: Cases of breast cancer in young women should raise a suspected diagnosis of Li-Fraumeni syndrome, which can change the therapeutic and investigation of other cancers at an early stage.

Introduction: Breast cancer is the second leading cause of death among women, affecting mainly the age group of 50–59 years, the age at which screening tests are recommended. However, it has shown a progressive incidence below 50 years. For this reason, the objective is to analyze the statistical data on early mortality from breast cancer up to 50 years, in view of possible losses in diagnosis and early management. Methodology: A descriptive epidemiological study, a retrospective of time series, using the data from the Mortality Information System (SIM) of the Health Surveillance Secretariat of the Ministry of Health (SVS/MS) in the period of 2010 and 2019, in Brazil and in the State of Goiás, was analyzed. Malignant neoplasms of death and women up to 50 years of age were included as causes of death. The data were compared and tabulated in Excel. Results: Deaths due to malignant breast cancer in Goiás, between 2010 and 2019, were 35 (20–29 years old), 306 (30–39 years old), and 766 (40–49 years old), equivalent to 26.2% of the total number of deaths in all age groups (1,107 cases). In Brazil, deaths were 1,149 (20–29 years old), 9,876 (30–39 years old), and 24,586 (40–49 years old), totaling 23.3%. Conclusion: According to the analysis, it is possible to point to an increase in deaths, especially for those aged 40–49 years. The lack of inclusion of women in this group interferes with the prognosis, since it makes the late diagnosis feasible and, in more advanced stages, causes less chances of cure. Possible adaptations and strategies for screening this public and coverage by public health systems must be considered.

Introduction: Breast cancer is the most common cause among women, with invasive ductal carcinoma (ICD) being the most prevalent and having great phenotypic and genotypic heterogeneity and the ability to metastasize. In turn, mastitis is an inflammation in the breast region, infectious or noninfectious causes, most commonly affecting lactating women. Objectives: It is intended to report a case of ICD accompanied by infectious mastitis and its reverberations. Case Report: A 27-year-old woman presents with a clinical history of mastitis in her left breast that occurred about 3 months ago after weaning her son. She also explained about the use of antibiotic therapy, multiple previous drainages, and local complication with engorgement, edema, erythema, and purulent drainage in the surgical ostium of the left breast. A new drainage and material collection was carried out. Computed tomography of the chest indicated a solid heterogeneous lesion, dense, irregular contours, with areas of air trapping, liquefaction, and cleavage plane with the left pectoralis major muscle and ipsilateral axillary adenomegaly. Pathological pathology confirmed the hypothesis of neoplasia, indicating grade III ICD in comedonecrosis. Immunohistochemistry demonstrated triple-negative character and culture, positivity for Corynebacterium renale. She started neoadjuvant chemotherapy with reduced breast volume and absence of secretion today. Discussion: This is a common and problematic situation in health systems. Repeated outpatient referrals, invasive processes without resolution, aggravating the patient’s case. Moreover, it is noted that mastitis has delayed the diagnosis of the neoplasm, which, depending on the delay, may result in a worse prognosis or a more aggressive or expensive treatment. Conclusion: The diagnostic investigation of neoplasms is of great importance in case of prolonged mastitis not responsive to treatment, due to the fact that many mastitides may come from neoplastic processes that generate the lesion, which can make this injured area conducive to bacterial proliferation.