In this study, the emissions to air produced using massive wood material in manufacturing of a Massiv-Holz-Mauer (MHM) wall system have been assessed. The results have been compared with a traditional brick wall. The sustainability of materials was determined using the following impact categories: global warming potential (GWP), ozone depletion potential (ODP), photochemical ozone creation potential (POCP) and human toxicity potential (HTP). Using wood material in building design can reduce the environmental impact to air up to 59 % compared to using traditional material such as brick. The major contributions to the emissions of the MHM wall production are related to the sawmill process, to the manufacturing of fibreboards and aluminium nails. Furthermore, a displacement factor of 0.52 t CO 2eq per ton of oven-dried wood for MHM building system used in place of the brick wall was determined for the considered system boundaries.