Background Infectious lung cavities are a common entity for the respiratory physician. Sometimes these lesions require surgical treatment, but surgery is challenging, and complications are common. Methods Patients with infectious lung cavities amenable to surgical treatment were included in a case-control study. The control group included patients with no complications. The cases group comprised patients with any of the following complications up to 90 days after surgery: death, persistence of hemoptysis, empyema, operative blood loss > 500 mL, vascular lesion requiring repair, massive transfusion (>5 units of packed red blood cells per 48 h) or reoperation for bleeding, postoperative mechanical ventilation, intensive care unit stay > 48 h, prolonged air leak, and persistent atelectasis. The potential risk factors for complications analyzed were demographic data, exposure to contaminants, comorbidities, preoperative embolization, surgical indication, spirometry results, and sputum test positive for Mycobacterium tuberculosis. Results Forty-five patients were included in the study and divided into 24 cases and 21 controls. We found a significant difference in the time to removal of chest tubes in favor of the noncomplicated cases (6.45 vs. 4.05 days, p = 0.030), and persistent active infection at the time of surgery tended to be a risk factor for complications (odds ratio = 6.6, 95% confidence interval: 0.7-60, p = 0.061). Conclusion The presence of persistent active infection at the time of surgery could be a risk factor for complications in resection surgery for infectious lung cavities.
Este artículo puede ser consultado en versión completa en http://www.medigraphic.com/neumologia RESUMEN. Introducción: El tumor fibroso solitario de la pleura representa menos del 5% de los tumores pleurales primarios, de 12 a 32% pueden tener comportamiento maligno con recurrencia local y metástasis. El estudio diagnóstico de elección es la tomografía computarizada de tórax. La mayoría se origina en la pleura visceral y son pediculados. El tratamiento es la resección quirúrgica en bloque por la alta probabilidad de recurrencia, con márgenes de 1-2 cm, 9% de los casos presenta recidiva. Objetivos: Identificar factores relacionados a comportamiento maligno y recidiva. Material y métodos: Estudio observacional, descriptivo, retrospectivo y transversal. Se incluyó a todos los pacientes sometidos a resección de tumor fibroso solitario de la pleura del Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Ciudad de México, de enero 2008 a diciembre 2017. Resultados: Se incluyeron 26 pacientes, la frecuencia mayor fueron tumores pediculados dependientes de la pleura visceral, 92% manifestó síntomas, principalmente disnea. Dieciocho benignos y ocho malignos, de los cuales dos recidivaron. Se presentó muerte asociada al tumor en dos casos. Conclusiones: Los factores relacionados a comportamiento maligno fueron la presencia de síntomas generales (p = 0.013), pérdida de peso mayor de 10 kg en los últimos seis meses (p = 0.004) e invasión a estructuras adyacentes (p = 0.020). Los factores relacionados a recurrencia fueron la presencia > 4 mitosis/10 campos de alto poder (p = 0.018), pérdida de peso mayor de 10 kg en los últimos seis meses (p = 0.046), invasión a estructuras adyacentes (p = 0.030) y resección quirúrgica subóptima (p = 0.003). El tumor fibroso solitario de la pleura es un tumor de comportamiento biológico incierto, por lo que deberán investigarse factores asociados a malignidad y recurrencia. El tratamiento es la resección quirúrgica en bloque y en caso de presentarse criterios de malignidad o recidiva se requiere terapia adyuvante.Palabras clave: Tumor fibroso solitario de la pleura, neoplasias pleurales, malignidad, recidiva. Fibrous solitary tumor of the pleura: Factors associated with malignant behavior and relapse Institutional experienceABSTRACT. Introduction: The fibrous lone tumor of the pleura represents less than 5% of the primary pleural tumors, from 12 to 32% can have malignant behavior with local recurrence and metastasis. The diagnostic study of choice is the computed tomography of thorax. Most originate in the visceral pleura and are pediculated. The treatment is surgical resection en bloc due to the high probability of recurrence, with margins of 1-2 cm. 9% of cases have recurrence. Objectives: Identify factors related to malignant behavior and recurrence. Material and methods: Observational, descriptive, retrospective and transversal study. All patients undergoing resection of TFSP are included in the National Institute of Respiratory Diseases, from January 2008 to December ...
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