Aspirin use after the diagnosis of CRC is independently associated with improved CSS and OS.

Human CD4 ؉ FoxP3 ؉ T cells are functionally and phenotypically heterogeneous providing plasticity to immune activation and regulation. To better understand the functional dynamics within this subset, we first used a combined strategy of subcellular fractionation and proteomics to describe differences at the protein level between highly purified human CD4 ؉ CD25 ؉ and CD4 ؉ CD25 ؊ T-cell populations. This identified a set of membrane proteins highly expressed on the cell surface of human regulatory T cells