This report describes a challenging obstetric case in which septic emboli from Streptococcus oralis endocarditis subsequently led to central nervous system infection. There were delays in diagnosis as the patient presented with non-specific symptoms of fever, diarrhoea and vomiting, initially suspected to be due to viral gastroenteritis and later SARS-CoV-2 infection. Antibiotics were commenced once gram positive cocci were isolated from a blood culture. The patient made no significant improvement despite antimicrobial therapy and subsequently developed a worsening headache and delirium. This deterioration was not rapidly recognised despite the use of a routine obstetric early warning score. However, a diagnosis of meningitis was made once the potential severity of the patient's condition was recognised and Streptococcus oralis was identified in cerebrospinal fluid and blood cultures. Bacterial endocarditis was diagnosed following transthoracic echocardiography. The patient improved with optimised antimicrobial therapy and delivered a healthy baby. This example highlights how non-specific symptoms can be caused by rare and life-threatening illnesses, and emphasises that early warning scores might not easily identify neurological deterioration in obstetric patients.
The initial management of transient ischaemic attacks (TIAs) effectively triages patients into either high or low risk categories. The literature demonstrates that the identification of high risk patients significantly reduces the subsequent risk of stroke. The administration of aspirin following a TIA reduces the risk of stroke by approximately 25%.A full cycle retrospective audit which included a baseline audit with two improvement cycles was completed. The notes of every patient presenting to Croydon University Hospital's emergency department (ED), who were subsequently diagnosed with a TIA were reviewed, with the aim of identifying areas for improvement and to implement sustainable long term interventions aimed to improve patient safety.The patient's notes were compared with the guidelines for the management of TIA. The baseline audit demonstrated results requiring an immediate intervention. A teaching session was provided for new FY2 doctors starting their emergency medicine rotations, which covered the initial management of TIA and the importance of following the local guideline.The first improvement cycle saw an improvement in all outcomes measured. A statistically significant improvement (P-value = 0.05) was seen in the documentation of symptoms in the prior week and the prescription of antiplatelets in the department. Furthermore, where only 31% of TIA patients received antiplatelets at the baseline measurement, 86% received this treatment during the first improvement cycle. This means that 55% more patients received improved initial management, subsequently reducing their stroke risk by 25%. Similar results were seen in the second improvement cycle, thus demonstrating the intervention had been both successful and sustainable.In conclusion, a simple intervention can provide significant and sustainable improvements to the management of TIA in the ED.
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