Terra firma-forme dermatosis (TFFD) is a bizarre, acquired and idiopathic dermatosis that etiology has still not been fully defined. It is characterized by the presence of asymptomatic, brownish dirt-like lesion maybe due to disorder of keratinization. These lesions cannot be removed with ordinary cleansing. Therefore, TFFD can be differentiated from dermatosis neglecta. Patient was a 17-year-old man with brownish lesions on his face for 1 month. The patient had a history of regular washing habit with soap and water. The lesions were asymptomatic however due to cosmetic reasons, the patient wanted to treat his skin lesions. Punch biopsy revealed hyperkeratosis and fungal spore are in stratum corneum. Salicylic acid peeling with alcohol base was performed on the patient's face. The skin lesions disappeared completely on gentle swabbing with peeling. In this point, the diagnosis of TFFD could be considered. Since, this disease can be confused with dermatosis neglecta, we report this case with literature review.

only conducted for 5 weeks period [5]. Recently, our group reported similar approach with treatment period of 3 months [6].Importance of fibroblast growth factor 9 (FGF9) in hair follicle regeneration has previously been reported [8]. Nevertheless, there is a lack of studies on FGF9 as a GFC component in human clinical trial. Based on previous reports, we investigated the therapeutic effect of GFC with FGF9 (Cellcurin) in AGA patients. Materials and methods Patient groupsA total of 18 patients with mild to moderate AGA were recruited for the present study after obtaining informed consent. We excluded the patients treated for AGA within a year and with infectious disease,