Pregnancy luteoma (PL) is a rare cause of non-neoplastic masses in pregnancy. PLs are usually asymptomatic. However, general symptoms like pelvic pain, lumbalgia, constipation or virilization due to active hormone secretion can be detected as the clinical findings of these benign cysts. The definitive diagnosis of PL is most commonly possible with a pathological evaluation after surgical intervention. Therefore, we present a successful management of PL with close follow-up until delivery. Beside the suspicion of malignancy by ultrasonography and magnetic resonance imaging (MRI), the cytological evaluation of ascites revealed benign cells which was helpful to decide expectant management.

HE-4 has also been studied in OC for its prognostic value. High levels of HE-4 was correlated with poor prognosis in OC with poor progression free survival [3,15]. In a recent metaanalysis, high levels of HE-4 was associated with advanced stage and serous subtypes. HE-4 was not significantly elevated in lymph node metastasis and high grades [15].