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Teratoma is a tumor representing differentiation from all embryonic germ layers, ectoderm, mesoderm, and endoderm. 1 Nasopharyngeal teratoma (NPT) can extend to the sphenoidal, endobuccal, and pharyngeal regions. The most common associated abnormality is cleft palate (CP). 2 A 14-month-old newborn girl was referred to our department for CP. Oral examination revealed a firm mass of 1 × 1.5 cm, appended to the ethmoid (Figure 1A). A head computed tomography scan revealed a well-delimited tumor with calcifications and fat tissue, expanding to the sphenoid (Figure 1C,D).

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Nasopharyngeal teratomas (NPT) are rare and represent only 2% of all teratomas. They can lead to an embryopathogenic mechanical obstacle responsible for a cleft palate (CP). We report the case of a 14-month-old female with NPT associated with a CP.