Glaucoma surgery is associated with a lower QoL in patients with early glaucoma due mainly to the psychological burden. In moderate and advanced glaucomas, the QoL scores did not differ between the surgical and the medical therapy groups.

PurposeWe sought to identify the utility values in a group of Brazilian patients with primary open-angle glaucoma (POAG), and to assess its impact on visual acuity (VA) and mean deviation index values.Materials and methodsThis was a cross-sectional study of consecutive patients with POAG, who were interviewed using three methods for obtaining utility values: time trade-off (TTO), standard gamble anchored at risk of death (SG1), and standard gamble anchored at risk of blindness (SG2). Visual function variables (VA and mean deviation index in the better eye) and sociodemographic characteristics (age, sex, race, and educational level) were also obtained for statistical analysis.ResultsThe mean age (± standard deviation) of the study population (n=227) was 65.7 (±15.1) years. Mean utility values for the entire population were 0.82 from TTO, 0.90 from SG1, and 0.93 from SG2 (P<0.0001). Age, race, and sex had no influence on the utility values. Higher education tended to predict higher values by TTO, but not by SG1 or SG2. Visual function variables had an influence on utility values. The more advanced the visual loss, whether measured by VA or perimetry, in the better eye, the lower the utility values by all three methods.ConclusionWe obtained utility values for Brazilian patients with POAG, as well as specific values for different levels of vision loss.

PurposeTo assess the quality of life of glaucoma patients under medical therapy with different prostaglandin analogs.MethodsA cross-sectional study of consecutive glaucoma patients was designed. We assessed the patients’ quality of life through the Brazilian 25-question version of the National Eye Institute Visual Functioning Questionnaire, comprising 12 subscales (general health, general vision, ocular pain, near vision, distance vision, social function, mental health, role limitations, dependency, driving, color vision, and peripheral vision) and a total composite score. Clinical features, including current medical treatment, were obtained from each patient’s medical record. Three groups of patients were identified according to the prostaglandin in use: bimatoprost, latanoprost, or travoprost. The main outcome measures were: mean score in each subscale and mean total composite score.ResultsThe mean total composite score for the whole group was 70.60. The bimatoprost, latanoprost, and travoprost groups had the following mean composite scores, respectively: 56.56, 77.36, and 71.08 (P = 0.001, analysis of variance [ANOVA]). Latanoprost and travoprost results were similar, and both were superior to bimatoprost. Most subscales had similar results. The subscale with the lowest score for all groups was general health. Groups were homogenous and comparable.ConclusionThere is a difference in the quality of life between glaucoma patients using prostaglandin analogs. It seems that bimatoprost users have lower QoL when compared to latanoprost and travoprost users.

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PurposeTo assess the impact of glaucoma therapy on utility values in a glaucoma population.MethodsA cross-sectional study of consecutive glaucoma patients was conducted. Utility values were obtained using the time trade-off method. Visual function variables (visual acuity and mean deviation in the better eye) and sociodemographic and clinical characteristics (age, sex, race, educational level, type of glaucoma, current and past glaucoma treatments, and comorbidities) were also obtained for statistical analysis. We divided the patients into three groups: medical treatment (group 1), surgical treatment (group 2), and mixed surgical and medical treatment (group 3).ResultsMean age of the study population (n=225) was 65.7 years. After controlling for glaucoma stage (early, moderate, and advanced), the difference among the groups in mean utility values was not statistically significant. Number of medications per patient, type of medication, or type of surgical technique did not have an impact on the utility values.ConclusionOur findings suggest that the type of therapy did not affect the utility values in a glaucoma population.