Background: It is not like where Tuberculosis patients live to be one of the global supporters of burden disease, especially in Indonesia. Economic problems are a trigger for low patient awareness in paying attention to living conditions. This incidence can be a supporting factor for the onset of RO TB. Objective: Knowing the home condition of Drug Resistant Tuberculosis (RO TB) patients. Method: Is an analytical research with a cross sectional approach. Analysis of the home physical condition of Drug Resistant Tuberculosis (RO TB) patients.Results: There are three variables of residential buildings, namely the type of residence, the wall of the dinggal, and the ceiling of the residence that meets the criteria standards of Law No. 01 of 2011. Conclusion: The home of RO TB patients is included in the category of meeting the requirements for a healthy residence so that there are other factors that cause RO TB in the patient's living environment.