Thyroid cancer is the most common among endocrine cancers. Over 90% of all thyroid malignancies are differentiated thyroid carcinomas (DTC). However, only 2%–13% of DTC present with bone metastasis. Radioactive iodine ablation (RAI) is the treatment of choice for metastatic DTC. However, RAI therapy is not as effective in bone metastasis as it is in lung and visceral metastases. Only few cases of surgical management of bone metastasis in DTC have been reported in the literature. Here, we report a case of follicular variant of papillary thyroid carcinoma with sternal and lung metastases, for which sternal metastatectomy was performed.

A 50-year-old man with carcinoma of the right buccal mucosa underwent staging whole-body 18F-fluorodeoxyglucose positron emission tomography–computed tomography, which revealed a hypermetabolic heterogeneously enhancing lobulated primary lesion in the right buccal region and an incidental finding of subacute stroke. The case highlights the importance of discriminating brain neoplasms mimicking stroke from true ischemic stroke, which is crucial for appropriate management of patients in an oncology setting.

Introduction: There is increasing anecdotal evidence that olfactory and gustatory dysfunction may be associated with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Aim: The aim of this systematic review and meta-analysis was to find the association of olfactory and gustatory symptoms with Coronavirus Disease-19 (COVID-19) and estimate their pooled prevalence. Materials and Methods: PubMed, Embase, EBSCO and Cochrane databases were searched for cross-sectional, cohort and case-control studies evaluating olfactory and gustatory symptoms in patients with COVID-19. The search terms included COVID-19, severe acute respiratory syndrome coronavirus-2, coronavirus, olfaction disorders, anosmia, hyposmia, dysgeusia and ageusia. Random effects model was used to calculate a pooled Odds Ratio (OR) and pooled prevalence. Results: Total 14 studies were included in qualitative synthesis and 13 studies were incorporated in quantitative synthesis, involving 3,125 patients. The pooled OR was 15.59 reflecting that smell and taste disorders were strongly associated with COVID-19. The pooled prevalence of olfactory and gustatory dysfunction was 56% and 44%, respectively. Conclusion: It can be concluded that there is a significant association between olfactory and gustatory symptoms and COVID-19. Majority of the studies support the use of these symptoms as screening tools for COVID-19.

Tobacco has been implicated as the strongest risk factor for oral malignancies and common potentially malignant disorders. Recent trend shows an increase in the prevalence of these lesions in non tobacco population. Studies suggest that clinicopathological features of leukoplakia differ in tobacco users and non users. Also, leukoplakia without known risk factors is at a higher risk of malignant transformation. Preliminary studies on carcinogenesis of non tobacco-associated head and neck cancers have identified a difference in the key genes involved in the pathogenesis of cancers associated with and without tobacco. While the genetic characterization of non tobacco oral cancers is gaining focus in the literature, there is a paucity of studies on non tobacco leukoplakia. An understanding of the non tobacco leukoplakia, possibly a distinct subgroup, may provide an insight into the inception of non tobacco oral cancers, leading to avenues for prevention, early diagnosis and precision medicine-led treatment approaches. Through this narrative review, authors revisit and summarize the existing literature on leukoplakia among non tobacco population.

Introduction: Health of individuals and community. Occupation, being a significant determinant of health, plays a vital role in the outcome of health. Mining being an occupation has it's own characteristics and occupational hazards. One such factor, being tobacco consumption has been sparsely reported among thermal power station workers. Aims and Objectives: To assess the prevalence of tobacco consumption among thermal power station workers in south India. Materials and Methods: Simple random sampling was used to collect data from the study in the subjects working in thermal power station. Pretested questionnaire was used to collect demographic and prevalence data pertaining to tobacco consumption. Descriptive statistical analysis was done for the data to express the same in frequencies. Results: Among the 401 study subjects, 121 of them consumed tobacco. Among them 59%(n=72) of them used smoking form of tobacco and about 23%(n=28) of them used smokeless form of tobacco. Vast majority73%(n=52) of the smokers used cigarette and 14%(n=19) used bidi. Conclusion: A significant number of workers in thermal power station were found to use tobacco. Further studies are required to be conducted on a larger scale followed by analytical studies to establish the strength of association between the occupation related variables and tobacco consumption.