Postpartum depression is a grave mental health problem, which is more prevalent than society realizes and poses great risk. It has been associated with lack of breastfeeding, aversion towards the baby and negative impact on the development of the child. A total of 300 women who delivered between January 14 to March 31 of 2020 at Saveetha Medical College and Hospital were chosen following ethical clearance. After explaining the aspects of the Edinburgh Postpartum Depression Scale in their native language, the questionnaire was provided. A score of 10 and above were considered positive. Data were evaluated using SPSS and Chi square test. The prevalence of PPD was seen in 14% of women. It was higher with vaginal delivery, in women who had multiple births, lack of financial and social support, with domestic violence and alcoholic partner. Medical help was advised to women who scored 10 and above; only 5% sought medical intervention. Others did not recognize depression as a health issue. This shows the lack of awareness among the population. Medical health professionals should spread awareness, conduct more studies to evaluate the prevalence, the predisposing factors, methods for early diagnosis and ways to help women overcome “THE OTHER SIDE OF MOTHERHOOD”.

IgA-dominant infection-related glomerulonephritis (IRGN) is a distinct morphologic variant of IRGN, characterized by dominant or codominant glomerular deposits of IgA, mostly in elderly and patients with diabetes. More cases are being reported in recent times due to increased awareness of the disease entity and increased rate of Staphylococcus infection. It usually presents as rapidly progressive renal failure with proteinuria, and treatment guidelines for this disease entity are not well defined. We report here 12 cases of IgA-dominant IRGN seen over a period of 5 years from a single center. Clinical features, biopsy findings, treatment, and outcomes were analyzed. Out of 12 patients, eight were males. The mean age of presentation was 52.4 ± 21 years. Skin was the most common site of infection seen in six patients. Gross hematuria was seen in 4 patients and 11 had nephrotic proteinuria. Eleven had low serum C3. Only two patients had diabetes. Methicillin-resistant Staphylococcus aureus (MRSA) was the most common organism isolated in six patients. Most common histopathology was crescentic glomerulonephritis seen in seven patients, followed by endocapillary proliferation in three and diffuse proliferative glomerulonephritis in two. Hemodialysis was done in eight patients and six patients received steroid therapy. End-stage renal disease developed in three patients, chronic kidney disease in three, and three patients died due to sepsis. Various infections including MRSA and Escherichia coli were associated with IgA-dominant IRGN both in patients with diabetes and nondiabetics. Suspicion and recognition of the disease is important as it has therapeutic and prognostic implications.

Background: Pregnant women are more susceptible to developing severe cases of COVID-19. They need to be more careful during the antepartum, intrapartum, and postpartum periods to prevent untoward outcomes. As no definite treatment for COVID- 19 has yet been proven,  the only effective approach to prevent unfavorable outcome is by increasing awareness of  COVID-19 among pregnant women and by encouraging them to follow the necessary prevention methods. This study was done to know, if the adherence to the recommended preventive practices were influenced by the knowledge and attitude of the mothers and whether having a good knowledge and attitude led to better adherence to prevention methods. It also aims to assess if current knowledge on the effects of COVID-19 infection on pregnancy among antenatal women is sufficient or if more efforts have to be taken to educate the mothers regarding the same. Aims: This research aims to assess the knowledge, attitude, and precautionary measures taken towards COVID-19 infection in pregnancy among antenatal women attending the outpatient clinic. Materials and Methods: It is a descriptive cross-sectional questionnaire-based study conducted in Saveetha Medical College Hospital from January 2021 to March 2021. All antenatal women attending the obstetrics outpatient clinic were included in the study. After obtaining their consent, each woman was given a semi-structured, pre-tested questionnaire to solve on the spot. The statistical analysis used were descriptive analysis, proportions, percentages, chi-square test, and Pearson correlation coefficient. Results: Among the 465 pregnant women included in the study, 86.02% had good knowledge of COVID-19 and its impact on pregnancy, 89.89% of women held a positive attitude towards battling the pandemic and 98.92% had good prevention practices against COVID-19 infection. There was a significant association between age and knowledge and a significant association between socioeconomic status with the knowledge, attitude, or preventive practices of the patients and between education level and attitude of the women at p<0.05. Knowledge, attitude and prevention were found to be strongly positively correlated indicating that with an increase in the knowledge there is an increase in attitude and practice of preventive measures by pregnant women. Conclusion: The women included in this study had adequate knowledge and a good attitude towards the impact of COVID-19 on pregnancy and lactation. They also take necessary precautionary methods to safeguard against acquiring COVID -19 infection.

BACKGROUND Endometrial carcinoma is a leading malignancy among females. Pre-operative imaging and biopsy are necessary to identify the disease. Clinicopathological analysis determines the extent of the disease. Complete surgical staging is advised for high-risk patients. The purpose of this study was to analyze the different clinical endpoints, prognostic factors and demographic details that will influence the survival patterns of the cases of carcinoma of endometrium who underwent surgery during the period from 2014 to 2017 at a tertiary care centre, Chennai, India. METHODS Patients diagnosed with operable endometrial carcinoma were surgically staged based on the surgical procedures performed namely, total abdominal hysterectomy (TAH) with bilateral salphingo-oophorectomy (BSO), bilateral pelvic lymph node dissection, and para-aortic lymphadenectomy (patients with high-risk features). Post-surgical staging specimens were histopathologically examined in the Department of Pathology. Adjuvant radiation was given to patients with stage IA grade II and above. Patients with stage III disease received adjuvant chemotherapy. Descriptive analysis was done to show the distributions of patients accordingly. Kaplan-Meier survival analysis was performed for the overall median survival of the patients. RESULTS The study consisted of a total of 35 patients with a mean age of 56 ± 8.64. Parameters such as age, clinicopathological features, stage (FIGO staging), tumor size, grade, lymphovascular invasion (LVI), myometrial invasion, cervical involvement, involvement of margins, lymph node ratio (LNR) and survival were studied. Tumor size and grade were found to be significant factors affecting the survival. Overall median survival period of patients who underwent surgery was found to be 31 months. CONCLUSIONS Tumor size and grade of the tumor are significant prognostic factors affecting the survival of the patients with carcinoma of endometrium. Lymph node ratio is a new concept in carcinoma endometrium to be pondered upon as a factor predicting survival in future studies thereby defining the role of lymph node dissection in surgical staging. KEYWORDS Endometrial Cancer, FIGO Staging, Lymph Node Ratio, Prognosis, Survival Analysis