Background : A stuck valve is the rare, highly lethal complication of mechanical prosthetic valves on oral anticoagulants, associated with signicant morbidity and mortality requiring emergency management. Methods : A prospective observational study was conducted on patients at cardiology department, Prathima institute of medical sciences (Karimnagar), who had recently developed stuck valves and were treated with streptokinase. We studiedResults : patients (n=44) receiving thrombolytic therapy with streptokinase between the period (12/2020 – 03/2022). The patients achieved 93.1% freedom from repeat operations or major complications. Haemorrhagic stroke occurred in two (4.5%) patients, a neurological decit in three (6.8%), an allergic reaction in one (2.25%), and death in one patient during therapy due to refractory cardiogenic shock (2.25%). Mortality was higher in haemodynamically unstable patients compared to those with haemodynamic stability. Thrombolytic therapy with streptokinase is a highly effective and safe treatment inConclusions : haemodynamically stable as well as unstable patients with stuck mechanic prosthetic valves

Introduction: Ibutilide is a class 3 antiarrythmic agent that is used infrequently. There are few studies on its usage, especially among Indians. Materials & Methods: A retrospective study was conducted on patients in a tertiary care unit who had recently developed atrial fibrillation and were given the normal dose of ibutilide. During the study period, data was gathered from medical records. Results: During the study period, ibutilide was given to a total of 40 patients who met the inclusion criteria. The majority of the participants were under 60 years old and had only been in atrial fibrillation for less than 24 hours. In 70% of cases, atrial fibrillation could be successfully terminated with only a small risk of adverse events. Conclusion: Ibutilide is a safe and effective treatment for people who have recent onset atrial fibrillation.

Interrupted aortic arch (IAA) is a rare congenital heart disease (CHD) which affects approximately 1.5% of CHD patients. It is a serious congenital vascular malformation and accounts severe mortality when associated with other intracardiac defects. This report describes the case of one day old infant with atresia of aortic arch presented with rapid breathing, poor feeding, and lethargy. The diagnosis of IAA and Ventricular septal defect (VSD) was made by two-dimensional echocardiography and conrmed intraoperatively which successfully corrected by immediate surgical intervention.