Acro-lentiginous melanoma, a pigmented lesion of the extremities, especially the palms and soles, is defined by a malignant tumor proliferation with high metastatic potential, which develops at the expense of melanocytes. Its incidence is constantly increasing and varies according to country and ethnicity. Its diagnosis is primarily histopathological, and its management remains multidisciplinary, where surgery and the plastic surgeon occupy a very important place. Our study consists of a retrospective descriptive study of 25 cases of acro-lentiginous melanoma. The average age of our patients is 60 years, with a male predominance. Plantar localization is predominant. All patients underwent extension workup and management consisted of surgical resection with safety margins followed by additional lymph node dissection and coverage of the resulting tissue loss. Through this study, we highlight the aggressive nature of acro-lentiginous melanoma as well as the importance of protocolized management of these melanomas.