Background/Aim. Renal stones located in the lower pole of kidney represent a serious challenge for surgical treatment in children. The options are: open surgery, extracorporeal shock-wave lithotripsy, percutaneous nephrolithotomy and retrograde intrarenal surgery. Reports about the endoscopic treatment in children are limited. The aim of the study was to evaluate the effectiveness of retrograde intrarenal surgery in pediatric patients with renal stones in lower pole of the kidney. Methods. We retrospectively analyzed the results of the retrograde intrarenal surgery in 24 patients with renal stones in lower pole, between April 2012 and April 2016. Flexible ureterorenoscopy in combination with holmium laser lithotripsy were performed. We considered stone fragment size 3 mm or less as a measure of sufficient fragmentation of the stone. Results. Mean duration of general anesthesia was 68 (range, 40-90) minutes. Duration