The fibrosis grade evolution was not worse in the coinfected patients. The immunosuppression absence and the shortest time period between the biopsies in the coinfected group are possible explanations.

Rapid tests (RT) have been widely used for screening of hepatitis C virus (HCV) in general population, but its performance in hemodialysis (HD) patients and mainly in kidney-transplant recipients (RTx) is less known. The aim of this study was to evaluate the accuracy of RT for detection of anti-HCV in HD and RTx patients. Patients were prospectively included subdivided in four groups according to the positivity for anti-HCV detected by conventional serology: (1) HD patients anti-HCV +, (2) HD patients anti-HCV −, (3) RTx patients anti-HCV +, and (4) RTx patients anti-HCV −. All patients were retested for HCV using the commercial kit Alere HCV® Bioeasy Rapid Test (Bioeasy Diagnóstica LTDA—Minas Gerais, Brazil) in capillary whole blood samples. During the period of study were included 46 HD patients anti-HCV+, 62 HD patients anti-HCV −, 53 RTx patients anti-HCV + and 56 RTx patients anti-HCV −. In patients on HD, the RT showed sensitivity (S), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), and accuracy of 100%. In RTx patients, S of 96%, SP of 100%, PPV of 100% and NPV of 97% were found (accuracy of 98%). In conclusion, in patients on HD there was 100% agreement between RT and the conventional immunoassay. In the RTx group, although the agreement was not 100%, the RT performed very well when compared to conventional serology. This study demonstrates that the RT can be an alternative to conventional serology in HCV screening of patients on HD and RTx.

Resumo INTRODUÇÃO:Mesenterite esclerosante (ME) é uma desordem rara e idiopática caracterizada por inflamação crônica da gordura mesentérica.Espectro de uma mesma doença, pode evoluir de inflamação inespecífica à fibrose e retração do mesentério. Sua prevalência varia de 0,16% a 7,80% e estudos referem associação com neoplasia maligna subjacente em 1 a 70% dos casos. Há discreto predomínio em homens, brancos, entre a 5ª e 7ª décadas de vida. Mecanismos fisiopatológicos sugeridos incluem cirurgia ou trauma abdominal prévios, doenças autoimunes, síndrome paraneoplásica, lesão isquêmica e infecção. A apresentação clínica depende do estágio de evolução da doença, podendo ser assintomática ou com sinais e/ou sintomas inespecíficos (dor abdominal, náusea e vômito, anorexia, febre, perda de peso, alteração do hábito intestinal, saciedade precoce e presença de massa abdominal). Geralmente tem curso benigno, estável ou de progressão lenta. O diagnóstico é estabelecido por avaliação histológica em paciente com achados radiológicos compatíveis (tipicamente uma