| The comparative efficacy of two oestrus synchronization protocols using Ovsynch and progestagen (TRIU -C ® ) was analysed based on the reproductive performance in Malabari cross bred goats. Early onset of oestrus with higher oestrus response was observed in the progestagen group of animals. However, there was no significant difference between the two protocols, on the duration and intensity of oestrus. When diagnosed by ultrasound sonography, the conception rate following the two protocols did not find to vary significantly. Even though, the intensity of oestrus did not vary with the protocols, the intensity was higher (P<0.05) in the conceived group of animals than those failed to conceive. This study suggests that the oestrus intensity has a correlation to the conception rate in goats. Keywords MATERIALS AND METHODS animalS and FeedingA total of 16 healthy Malabari crossbred multiparous goats aged between 3-4 years and body weight around 20-25 kg were selected for the study. The animals were exposed to natural lighting conditions at latitudes between 11°47' N & 15°58' N, where maximum temperature and relative humidity is ranging between 27-29 o C and 78-88 mm/Hg respectively during the breeding season. They were fed with a daily ration of 200 g concentrate mixture per animal (Table 1). In addition, free access to green grass and water was made available. Synchronization ProtocolSThe goats were divided into two groups of eight animals each. Goats belonging to Group I were subjected to oestrus synchronization by using Ovsynch Protocol with first dose of Buserelin injection (0.004mg), GnRH analogue (1ml Receptal ® , Intervet, Holland) on day 0 intramuscularly followed by an intramuscular injection of prostaglandin (12.5 mg) Dinoprost (2.5 ml Lutalyse ® , Pfizer, Belgium) on 7 th day. Forty eight hours after prostaglandin treatment (day 9 th ), a second dose of Buserelin (0.004mg) was again administered intramuscularly. grouP i (ovSynch Protocol)Animals in Group II were subjected to the intra-vaginal placement of progesterone device (TRIU-C ® , Virbac, India) containing 160 mg of natural progesterone along with intramuscular injection of GnRH (Buserelin,0.004 mg) on the first day of the experiment (day 0). The intravaginal device was retained for seven days and at the time of withdrawal (day 7 th ) an intramuscular injection of 12.5 mg of Dinoprost, an analogue of PGF 2α (2.5 ml Lutalyse ® , Pfizer, Belgium) was administered. grouP ii (ProgeStagen-triu-c ® Protocol)Twenty four hours after the prostaglandin treatment the goats in each group were exposed to apronised bucks for 30 minutes for detection of oestrus and its scoring. The Flehmen's reaction shown by the teaser buck was primarily observed and the intensity of oestrus signs in does was determined ( Table 2). The goats were inseminated with fresh semen 72 hours (day 10 th ) after the administration of the prostaglandin injection and re-inseminated twenty four hours after the first insemination (day 11 th ). The does were observed for the onset ...

| Successful oestrous synchronization protocol must support a reasonable level of pregnancy in the synchronized cycle. Premature luteal regression and a drop in progesterone, the pregnancy hormone and concentration is a common phenomenon in goats following oestrus synchronization. Therefore, this study was undertaken to evaluate the comparative efficacy of two oestrus synchronization protocols on the progesterone profile of the Malabari cross bred goats which would be of practical significance for estrous synchronization of goats. It was observed in this study that the progesterone profile in goats did not vary with the treatment regimens to which they were subjected. Curiously, we observed that the progesterone concentrations on the day of insemination showed significant difference (P<0.05) between the goats those conceived and those failed to conceive. We could make the earliest detection of pregnancy using progesterone estimation by ELISA by day 17 th post insemination, while it could be confirmed only on day 20 th by ultra-sonography.

The COVID’19 pandemic, recent spike of Omicron variant and the upsurge in air pollution in metropolitan cities like Delhi has highlighted the importance of oxygen cylinders andother equipment’s. The various units in the health system such as: General wards, Emergency transport, Delivery rooms, Operatingtheaters, Intensive care units (ICU) also require a regular supply of oxygen. Thus, timely and powerful planning for reliable oxygensupply and delivery is needed to protect and save lives of people who are in need. Due to the unavailability of a proper channel of acquiring Oxygen during the pandemic, forced people to search for the supply of oxygen through phone calls and various social media platforms. But only few people got reliable suppliers and many could not get their demand satisfied at the right time. Evenhospitals faced the same situation. To combat such problems,in this project we propose a unique system for Oxygen Supply Management to people and hospitals which can meet the crisisin an effective way. In order to overcome the shortage of oxygen in the coming times, this proposed system will be launched as a digital platform to fast-pace the supply chain to both people and hospitals. Index Terms: Covid-19, pandemic, Omicron