Background: Tinea is a common fungal infection seen in the tropical and subtropical countries affecting the skin and its appendages. The presentation may vary from mild scaling to severe inflammation with bacterial super infection. It may be confused with other manifestation such as psoriasis, seborrhea, drug eruptions, eczema, and contact dermatitis. Hence correct diagnosis is necessary for appropriate treatment, which will reduce morbidity, discomfort and lessens possibility of transmissions. The aims and objectives were to determine clinicomycological profile of Tinea infections in patients attending dermatology OPD of B. J. Govt. Medical College and Sassoon General Hospital, Pune. Methods: Skin scrapings, nail clippings; hair samples from clinically suspected cases of tinea were collected. Identification of dermatophytes from these samples was done by conventional technique. Results: 119 clinically suspected cases of Tinea infections were processed over a period of one year. Out of these cases mixed infection of Tinea cruris with corporis was the predominant (27.73%) clinical presentation. Among all the samples, fungal filaments were seen by KOH mount in 48 (40.33%) whereas 35 (29.41%) samples were confirmed as dermatophytes by culture. Among these 35 isolates of dermatophytes 20 were T. rubrum, 7 isolates were T. tonsurans. 8 isolates were of T. mentagrophytes. Conclusions: In present study mixed infections of tinea cruris with corporis was the predominant clinical presentation and T. rubrum was the most common dermatophyte isolated.

Background: The cases of dermatophytoses have increased over the past few decades. Dermatophytoses affect the outer layers of skin, nails and hairs without tissue invasion. These infections are mostly not dangerous but, are important as public health problem particularly in the immunocompromised. The increased use of antifungal drugs for prolonged periods may lead to acquired antifungal resistance among previously susceptible strains. With this background present study was conducted to know the susceptibility pattern of dermatophytes. Methods: A total 35 isolates of dermatophytes isolated from clinically suspected cases of dermatophytoses were examined. Broth microdilution method M38-A2 approved protocol of CLSI (2008) for filamentous fungi was followed for determining the susceptibility of dermatophyte species to antifungal agents-itraconaole, fluconazole and ketoconazole. Results: Itraconazole minimum inhibitory concentrations (MIC) varied from 0.0156 to 1 µg/ml for all dermatophytes. T. rubrum species showed higher MIC range for Ketoconazole than T. mentagrophytes and T. tonsurans. Fluconazole had poor susceptibility for all dermatophytes by having higher MIC values. Conclusions:The MIC values observed in present study will help clinician to select an appropriate antifungal agent with minimal side effects. The data from present study can be useful as reference for future studies covering large no. of isolates and more drugs.