Baricitinib rapidly relieves eczema associated pruritus in elderly patientsDear Editor, Pruritus in the elderly has many causes including primary skin disorders, systemic diseases, drugs, and neurological and psychiatric disorders. 1 Regardless of the cause, the incidence of pruritus increases with age, and the burden of this condition has a negative impact on quality of life. 2,3 The condition is often refractory to conventional treatments such as antihistamines, corticosteroids, and cyclosporine, and their use is limited due to the comorbidities of elderly patients.

Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder worldwide. Its pathogenesis encompasses various immune responses and associated inflammations. Not only type 2 inflammatory pathway, which is the dominant pathway of AD, but also types 1 and 3 inflammatory pathways are also revealed to be involved in the disease pathogenesis. 1,2 Due to its complex pathophysiology, it was challenging to manage only with available treatments. 3 With advances in the understanding of disease mechanisms, however, novel potential therapeutic options have been emerging in recent years. The first