No abstract

In this multicenter study of 328 twin pregnancies with Type-III selective intrauterine growth restriction (sIUGR), fetal death complicated 11% of them. At viability, mortality rates were very low (< 2% at 28 weeks). Delivery at 32 weeks was associated with a high rate of adverse neonatal outcome, which substantially decreased at 34 weeks (11%), with a very low risk of fetal death (0.7%). What are the clinical implications of this work? With close fetal surveillance, the risk of unexpected fetal death in Type-III sIUGR may be lower than reported previously. Further multicenter studies are needed to assess which factors truly predict fetal death, in order to allow for optimal pregnancy management.

Our results show that first trimester PE screening in our population performs well and according to expectations, whereas screening for SGA is associated with a high false positive rate.