En la actualidad, las Pymes enfrentan una necesidad notable de transformar su gestión innovadora; por lo tanto, es necesario encontrar las herramientas que potencien toda su capacidad. Para impulsar nuevas prácticas de innovación con visión abierta, es fundamental que la cultura organizacional se transforme a una cultura de innovación, para que pueda adaptar nuevas estrategias y herramientas que generen un cambio de mentalidad y se visualice a las empresas como una comunidad de oportunidades, de conocimiento y crecimiento. Este estudio tiene como objetivo encontrar información que ayude a crear una propuesta de un modelo de innovación abierta, basado en la realidad de las Pymes del sector comercial de venta de partes, piezas y accesorios para vehículos. Se levantaron datos utilizando encuestas cara-a-cara a una muestra aleatoria de los locales comerciales en estudio de la ciudad de Cuenca. La información recolectada condujo a observar los resultados de una baja implementación innovadora en las PYMES de este sector y permitió identificar herramientas que se proponen como una innovación abierta para que se viabilice y direccione de una manera adecuada la información de fuentes internas y externas, para alcanzar mejores resultados que impulsen el crecimiento de las Pymes. Palabras clave: cultura innovadora, gestión empresarial, innovación abierta, oportunidad, Pymes. Abstract

Methods of providing nutrition and physical activity (PA) education for individuals with obesity-related chronic illnesses can be difficult to address in a primarily agricultural region where seasonal work schedules, limited medical resources, and geographical distances are significant barriers. To examine the feasibility of a program using online live Zoom-delivered sessions and text messaging in such a setting, we adapted an evidence-informed in-person intervention previously shown to be effective in urban Latino cancer survivors. Nineteen Spanish-speaking Latino women and one man were recruited to a single-arm intervention. Over 3-months, the intervention delivered 6 biweekly 2-hour interactive sessions led by a community health educator and a trained chef plus 4 text messages per week focused on nutrition and PA. All participants were given a Fitbit for self-monitoring PA and access to the Cook for Your Life bilingual website, which provides health recipes for cancer survivors. Preliminary assessments occurred using a pre-post study design. Sixty-five percent of the sample completed at least half of the sessions, 95% completed the data collection and found the check-in phone calls somewhat or very helpful. 100% indicated the live interactive educational sessions and the text messages were somewhat or very helpful. Eighty-four percent of participants found the FitBits and 63% found the website useful. Preliminary outcomes, significant lessons learned, and adaptations implemented accommodate the rural setting and online format, insights gained by participants during an exit interview, and implications for future research such as the exclusive use of smart phones to engage in the intervention, will be discussed. Citation Format: Rachel M. Ceballos, Sofia Cobos, Eileen Rillamas-Sun, Oscar Sanchez, Jayleen Ceja, Genoveva Ibarra, Allison Silverman, Katherine Guthrie, Heather Greenlee. Adaptation and feasibility of a Spanish language nutrition and physical activity online intervention for rural-dwelling Latinos with obesity-related chronic diseases [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr B021.

650 Background: Regular moderate to vigorous physical activity (MVPA) in patients with gastrointestinal (GI) cancers is associated with improved health outcomes, including greater quality of life and reduced fatigue and comorbidity. PA guidelines for cancer survivors recommend ≥150 minutes of MVPA per week for optimal health. Identifying GI oncology patients with low MVPA is important to tailor interventions aimed at increasing MVPA levels in this population. The “Exercise as a Vital Sign” (EVS) tool is a validated, two question assessment tool to quantify minutes per week (min/wk) of MVPA that was incorporated in the clinical rooming process at an academic GI oncology clinic. Here, we report characteristics of patients by amount of MVPA by EVS. Methods: Patient information was entered in the electronic medical record at a large, academic oncology clinic. Data from the first clinic visit where min/wk of MVPA EVS was collected were extracted and included demographics (e.g. age, sex, marital status, race), health status (body mass index (BMI), Eastern Cooperative Oncology Group (ECOG) performance status, comorbidities), cancer characteristics (primary tumor site, localized/metastatic, current treatment), and reason for the clinic visit. MVPA was divided into two groups based on the recommended guidelines: 0-149 min/wk (“low”) and ≥150 min/wk (“high”). Chi-square and t-tests were used to examine statistically significant differences. Results: Among 265 patients abstracted, EVS data were reported from 156 (59%) patients. Mean (standard deviation (SD)) age was 61 (13) years (range: 25-82). The primary cancer site was 35% colorectal, 23% pancreatic, 17% gastroesophageal, 10% neuroendocrine, and 15% other GI cancers. While gastroesophageal cancer patients reported high amounts of MVPA (mean (SD) = 268 (309) min/wk), comparisons with other cancer sites were not statistically different. Of the 156 with EVS data, 84 (54%) had low MVPA (mean (SD): 55 (49) min/wk) and 72 (46%) had high MVPA (mean (SD): 357 (244) min/wk). Demographic and cancer characteristics were similar across the two groups. Patients with high MVPA were more likely to have BMI 18.5-24.9 kg/m2 (56% vs. 31%) and less likely to have BMI ≥25 kg/m2 (40% vs.61%) compared to patients with low MVPA (p = 0.02). Patients with high vs. low MVPA were also more likely to have excellent performance status (ECOG 0; 47% vs. 24%, p < 0.001). Conclusions: In this study, GI oncology patients not meeting PA guidelines for cancer survivors were more likely to be overweight/obese and have worse performance status. The EVS tool was an inexpensive and accessible measure of MVPA that can be used to identify patients with low MVPA for interventions targeted to improve health outcomes. A lack of statistical significance may be due to low power. At the conference, more data will be presented (̃1000 patient visits), including longitudinal data and MVPA by active chemotherapy regimen.

Purpose: Cook for Your Life (cookforyourlife.org) is a bilingual, science-based nutrition and culinary website designed for cancer patients and survivors based at the Fred Hutchinson Cancer Research Center. The website has been used as a tool and resource for health intervention research. This analysis described the characteristics of English and Spanish language users who responded to an online survey. Methods: Visitors to cookforyourlife.org were invited to participate in an online survey collecting demographic characteristics and health behaviors. Those at least 18 years old were eligible. Respondents with a cancer diagnosis were asked a subset of questions about treatment and side effects. English language (EL) and Spanish language (SL) versions launched in December 2020 and April 2021, respectively. Survey data were analyzed through October 2021 and only included those completing at least 50% of the survey questions. Demographic characteristics from web analytics data were compared. Results: Among EL respondents, 3039 initiated the survey and 2417 completed at least 50% of the questions. Of these, 53% were persons with a cancer diagnosis, 8% were caregivers of cancer patients, and 39% other. The majority of EL respondents were US residents (77%), but many were also from Europe (11%) and Canada (6%). Cancer patients/survivors were most likely to be ≥55 years old, female, non-Hispanic white, have income &gt;$100K, and be college educated. Caregivers and others were younger, but otherwise had similar demographics. Among cancer patients/survivors, 46% had breast cancer and 7% pancreatic and 49% reported having treatment side effects in the past week, with 31% citing fatigue and 15% anxiety. Among SL respondents, 804 initiated the survey and 545 were eligible for analysis. Of these, 17% were cancer patients/survivors, 8% caregivers, and 75% other. SL respondents were also more likely to be female and highly educated, but were younger, from South/Latin America, and had income &lt;$30K. Among SL cancer survivors, 31% had breast cancer and 8% had colorectal. Web analytics data on 1.5+ million visitors from December 2020 to October 2021 indicated most visitors were 71% female and lived in South/Latin America (35%) or the US (31%). Conclusions: Respondents of the Cook for Your Life English-language website survey were predominantly US women with high socioeconomic status; many had history of breast cancer. Conversely, Spanish-language respondents had more socioeconomic diversity, but fewer were diagnosed with cancer. Web analytics data suggested survey respondents may differ demographically from general website users. Knowledge about our website users is necessary for developing targeted strategies to improve reach. Future research efforts will focus on delivering content to more varied populations of cancer patients and survivors, their caregivers, and individuals interested in cancer prevention. Citation Format: Eileen Rillamas-Sun, Liza Schattenkerk, Sofia Cobos, Kate Ueland, Heather Greenlee. User characteristics of “Cook For Your Life” - a website designed to support cancer patients and survivors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5905.

Purpose: The Cook & Move for Your Life randomized pilot study assessed the feasibility and relative efficacy of two dose levels of a remotely-delivered diet and physical activity (PA) intervention for breast cancer (BC) survivors. Methods: Women with a history of stage 0-III BC who were &gt;60 days post-treatment, ate &lt;5 servings per day of fruits/vegetables or engaged in &lt;150 minutes per week of moderate to vigorous physical activity (MVPA), and had smartphone or computer access were enrolled. Participants were randomized to receive one of two doses of an online diet and PA didactic and experiential program, with outcomes measured at 6 months. The low-dose arm received a single 2-hour Zoom session delivered by a dietitian, a chef, a culinary educator, and an exercise physiologist; the high-dose arm received 12 2-hour Zoom sessions over 6 months. All participants received weekly motivational text messages, a Fitbit to self-monitor PA, and study website access. The primary objective was to evaluate overall feasibility based on accrual, adherence, and retention. Prespecified feasibility endpoints were 75% retention at 6 months and 60% of high-dose arm participants attending at least 8 of the 12 sessions. Secondary objectives were to compare high vs. low dose intervention effects on 6-month changes in fruit/vegetable servings per day (24-hour dietary recall), MVPA minutes per week (accelerometry), and blood and stool biomarkers. Results: From December 2019 to January 2021, 74 women were accrued. On average, women were 57.9 years old, 4.8 years post-diagnosis, with body mass index of 29.1 kg/m2. Most were non-Hispanic white (89.2%), 51.4% were diagnosed at stage I, and 40.5% were on endocrine therapy. Questionnaire and biospecimen data collection at 6-months were completed for 93.2% and 83.8% of the sample, respectively. In the low-dose arm (n=36), 94.4% of participants attended the single class, while in the high-dose arm (n=38) 84.2% of participants attended at least 8 of the 12 sessions live or via video archived on the website (mean 9.4 sessions). On average over the 6-month intervention period, participants responded to 71.5% of the text messages, 73.0% wore their Fitbit device ≥50% of the time, and 77.0% accessed the study website. Mean vegetable intake increased by 1 serving per day among women in the high-dose arm and decreased slightly among women in the low-dose arm (P=0.03). Changes in fruit/vegetable intake and MVPA varied little by arm. Blood and stool biomarker analyses are ongoing. Conclusion: We successfully conducted a remotely-delivered diet and PA intervention for BC survivors with high accrual, adherence, and retention during the COVID-19 pandemic. Women in the high-dose arm increased vegetable intake relative to the low-dose arm. Future research will refine and test the intervention in a larger and more diverse study population. Citation Format: Heather Greenlee, Rachel Yung, Sofia Cobos, Eileen Rillamas-Sun, Hanjie Shen, Yuhan Huang, Sidney M. Donzella, Liza Schattenkerk, Kate Ueland, Matthew VanDoren, Samantha Myers, Theresa King, Margarita Santiago-Torres, Chongzhi Di, Neel Dey, Katherine A. Guthrie, Nancy E. Davidson. Cook and Move for Your Life: A pilot study of an online intervention to improve diet and physical activity among breast cancer survivors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr CT509.