Objective:The aim of our study was to compare the values of blood pressure (BP) and pulse pressure (PP) in the brachial artery and in the central aorta by outpatient non-invasive methods in different patients age groups and according to the presence of chronic renal disease and diabetes.Design and method:The study included 110 outpatients older than 18 years of age with diagnosed and treated arterial hypertension (AH), under the care of Clinical Hospital Centre Rijeka in the period from June 1 to December 1, 2021. Peripheral BP, PP, and central aortic pressure (CAP) were measured in all patients on the same day. The average values of peripheral arterial pressure and the corresponding PP were obtained by the method of continuous blood pressure monitoring (CBPM). CAP and associated PP were measured on the same day by the method of radial arterial tonometry. Patients were divided into three groups according to the age (18–44 years, group I; 45–64 years, group II, and > 65 years, group III). Systolic and diastolic peripheral blood pressure (SPBP, DPBP), systolic CAP and diastolic CAP (SCAP, DCAP), and both peripheral and central PP (PPP, CPP) were nalysed among groups and according to the presence of chronic kidney disease (CKD).Results:In total, 98 patients were nalysed (mean age 55,08 ± 15,52 years; 79,6% essential hypertension; diabetics 12,23%; 26,53% CKD; 48,98% men). There were significant positive correlations between SPBP and SCAP, DPBP and DCAP, and PPP and CPP in group I and group III. There was no significant correlation between SPBP and SCAP (r = 0,268), and there were significant correlations between DPBP and DCAP, and PPP and CPP in group II. According to the presence of CKD, there was no significant correlation between SPBP and SCAP (r = 0,104), and there were positive correlations between DPBP and DCAP, and PPP and CPP.Conclusions:There was no significant correlation between SPBP and SCAP in 45–65 years old and CKD group, which tells us in favor of the atherosclerosis variability in these patient groups, which was expected. Further research on greater number of patients should be done.