Background and aims Diabetes is a frequent comorbidity in patients with Severe COVID-19 infection associated with a worse prognosis. Hypercoagulability with elevation in D-dimer levels has been demonstrated in patients with COVID-19. This study aims to study D-dimer levels in people with diabetes compared to those without diabetes among patients with COVID-19 infection. Methods In this observational study 98 moderate and severely ill patients with COVID-19 infection were included at a dedicated COVID hospital. The study group was divided into patients with diabetes and without diabetes. Peak D-dimer was measured in both the groups and compared using appropriate statistical tests. Results In our study peak D-dimer levels were 1509 ± 2420 ng/mL (Mean ± SD) in people with diabetes and 515 ± 624 ng/mL (Mean ± SD) in patients without diabetes. Patients with diabetes had higher D-dimer levels which were statistically significant. Conclusions This study shows COVID-19 patients with diabetes had significantly higher D-dimer levels. Therefore, it is possible that COVID-19 infection with diabetes is more likely to cause hypercoagulable state with a worse prognosis. However clinical implications of these findings will need to be seen in further studies.

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In this work, we calculate the Hawking temperature for a quantum corrected black hole geometry using the reflection from the horizon method. We observe that quantum gravity corrections indeed show up in the Hawking temperature formula of the quantum corrected black hole. It is important to notice that the quantum gravity corrections arise in the Hawking temperature formula only due to the underlying quantum gravity corrections to the lapse function of the black hole metric rather than the semi classical methods used in the analysis. We also substantiate our result by computing the Hawking temperature using the tunneling approach.