An efficient, fast, and green synthesis of benzimidazolo/benzothiazolo quinazolinone derivatives has been developed under solvent‐free conditions by the reaction of 2‐aminobenzimidazole/2‐aminobenzothiazole, aromatic aldehydes, and 1,3‐diketones. This method extended the application of microwave irradiation and scandium triflate combination and also tenders a lot of benefits such as excellent product yields, shorter reaction time, easy isolation of products, and environmentally benign reaction conditions.

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The present report highlights an efficient use of oxygen radical anion to promote a room temperature multi-component synthesis of spirooxindoles (4a–4l) under mild reaction conditions. The potassium superoxide (KO2) and tetraethylammonium bromide (TEAB) combination generate the oxygen radical anion in situ to promote this transformation. This method offers a sustainable and direct access to the biologically important spirooxindole derivatives in good to excellent yields.

A straightforward strategy has designed for the efficient synthesis of 2,4,6-triarylpyridinesvia a three component reaction of acetophenone, methyl arenes and ammonium acetate. The total transformation is successfully achieved using a magnetic nano-Fe 3 O 4 . The method developed is sustainable, using low cost feed stocks, operationally simple, and provide good to excellent yields.

We herein report the Et3N catalyzed sp3 C−H bond functionalization of methyl arenes with active methylene compounds under solvent‐free condition using TBHP as an oxidant. These reactions are exclusively enabled by TBHP. The methyl arenes used in this reaction are highly versatile and rapidly undergo oxidation and further condensation with malononitrile /ethylcyanoacetate. This is a metal‐free, practical, inexpensive, non‐toxic and environmentally benign method.